Hepatic splenosis mimicking HCC in a patient with hepatitis C liver cirrhosis and mildly raised alpha feto protein; the important role of explorative laparoscopy


Abu Hilal, M., Harb, A., Zeidan, Bashar A., Steadman, B., Primrose, J. N. and Pearce, N. W. (2009) Hepatic splenosis mimicking HCC in a patient with hepatitis C liver cirrhosis and mildly raised alpha feto protein; the important role of explorative laparoscopy. World Journal of Surgical Oncology, 7, (1), 1-4. (doi:10.1186/1477-7819-7-1).

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Original Publication URL: http://dx.doi.org/10.1186/1477-7819-7-1

Description/Abstract

Background:

Splenosis is a heterotropic implantation of splenic fragments onto exposed vascularised peritoneal and intrathoracic surfaces, following splenic injury or elective splenectomy.

Case presentation:

A 60 year old cirrhotic patient was referred to us with a hepatic mass, suspected to be HCC in a cirrhotic liver. A computerized tomography scan (CT) demonstrated a
cirrhotic liver with a 2 × 2.7 cm focal hypervascular nodule, lying peripherally at the junction of
segment 7 and 8.

Diagnostic laparoscopy demonstrated a 3 cm exofitic dark brown splenunculus attached to the diaphragm and indenting the surface of segment 7 of the liver. The lesion was easily
resected laparoscopically and shaved from the live surface with no need for a liver resection.

The histopathological assessment confirmed the diagnosis of splenunculus, with no evidence of neoplasia.

Conclusion:

Hepatic splenosis is not a rare event and should be suspected in patients with a history of splenic trauma or splenectomy. Correct diagnosis is essential and will determine subsequent management plans.

In doubtful cases laparoscopic investigation can offere essential information and should be part of the standard protocol for investigating suspected splenosis.

Item Type: Article
Related URLs:
Subjects: R Medicine > RD Surgery
Divisions: University Structure - Pre August 2011 > School of Medicine > Cancer Sciences
ePrint ID: 144847
Date Deposited: 15 Apr 2010 10:19
Last Modified: 27 Mar 2014 19:06
URI: http://eprints.soton.ac.uk/id/eprint/144847

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