Total synthesis of annonaceous acetogenins belonging to the non-adjacent Bis-THF and non-adjacent THF-THP sub-classes
Spurr, Ian B. and Brown, Richard C.D. (2010) Total synthesis of annonaceous acetogenins belonging to the non-adjacent Bis-THF and non-adjacent THF-THP sub-classes. Molecules, 15, (1), 460-501. (doi:10.3390/molecules15010460).
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Description/Abstract
The synthesis of the subgroups of acetogenins containing non-adjacent bis-THF and non-adjacent THF-THP core units is reviewed. Specifically, total syntheses of gigantecin, 4-deoxygigantecin, cis-sylvaticin, squamostatin-C, squamostatin-D, sylvaticin and mucocin are discussed.
| Item Type: | Article |
|---|---|
| ISSNs: | 1420-3049 (electronic) |
| Related URLs: | |
| Keywords: | annonaceous acetogenins, non-adjacent bis-THF, tetrahydrofuran, tetrahydropyran, asymmetric synthesis, 1,2-diols, epoxides, cytotoxic natural products, anti-tumour |
| Subjects: | T Technology > TA Engineering (General). Civil engineering (General) |
| Divisions: | University Structure - Pre August 2011 > School of Chemistry |
| Item ID: | 148877 |
| Date Deposited: | 29 Apr 2010 08:36 |
| Last Modified: | 01 Jun 2011 07:44 |
| Contributors: | Spurr, Ian B. (Author) Brown, Richard C.D. (Author) |
| Date: | 2010 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/148877 |
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