Lung metastasectomy in colorectal cancer: Is this surgery effective in prolonging life?
Lung metastasectomy in colorectal cancer: Is this surgery effective in prolonging life?
The commonest context in which pulmonary metastasectomy is performed is for recurrent colorectal cancer. With a more active policy of surveillance among cancer teams, ready access to ever faster CT scans and a willingness to perform further surgery to control recurrent cancer, the practice of pulmonary metastasectomy is increasing. In this pro/con debate the issues are explored. It is recognized by both sides that there is no randomized trial evidence on which to base the practice. The difference of opinion is whether there is sufficient evidence from very many case series of both pulmonary and hepatic metastasectomy on which to base current practice. The surgeon's view is that the weight of evidence from many follow-up studies is in favour of continuing this practice. The mathematician's view is that case selection could account for nearly all the observed results.
colorectal neoplasm, neoplasm metastasis, recurrence, thoracotomy
1-5
Primrose, John
d85f3b28-24c6-475f-955b-ec457a3f9185
Treasure, Tom
824addc5-0a4f-44c9-8ec2-5b2f3dda2207
Fiorentino, Francesca
e7bed6cb-dccf-437d-b58d-844bfc4e280a
23 April 2010
Primrose, John
d85f3b28-24c6-475f-955b-ec457a3f9185
Treasure, Tom
824addc5-0a4f-44c9-8ec2-5b2f3dda2207
Fiorentino, Francesca
e7bed6cb-dccf-437d-b58d-844bfc4e280a
Primrose, John, Treasure, Tom and Fiorentino, Francesca
(2010)
Lung metastasectomy in colorectal cancer: Is this surgery effective in prolonging life?
Respirology, .
(doi:10.1111/j.1440-1843.2010.01759.x).
Abstract
The commonest context in which pulmonary metastasectomy is performed is for recurrent colorectal cancer. With a more active policy of surveillance among cancer teams, ready access to ever faster CT scans and a willingness to perform further surgery to control recurrent cancer, the practice of pulmonary metastasectomy is increasing. In this pro/con debate the issues are explored. It is recognized by both sides that there is no randomized trial evidence on which to base the practice. The difference of opinion is whether there is sufficient evidence from very many case series of both pulmonary and hepatic metastasectomy on which to base current practice. The surgeon's view is that the weight of evidence from many follow-up studies is in favour of continuing this practice. The mathematician's view is that case selection could account for nearly all the observed results.
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Published date: 23 April 2010
Keywords:
colorectal neoplasm, neoplasm metastasis, recurrence, thoracotomy
Identifiers
Local EPrints ID: 149405
URI: http://eprints.soton.ac.uk/id/eprint/149405
ISSN: 1323-7799
PURE UUID: f7e02b67-b19e-43cd-bc73-45e566462753
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Date deposited: 30 Apr 2010 08:56
Last modified: 14 Mar 2024 02:37
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Author:
Tom Treasure
Author:
Francesca Fiorentino
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