Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential?

Nolan, L., Johnson, P.W.M., Ganesan, A., Packham, G. and Crabb, S.J. (2008) Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential? British Journal of Cancer, 99, 689-694. (doi:10.1038/sj.bjc.6604557).

Record type: Article

Abstract

Histone deacetylase inhibitors have progressed rapidly from the laboratory to clinical testing. This review highlights the promising data for their combination with a wide range of established and novel anticancer agents and discusses the mechanisms that underpin these interactions.

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More information

Published date: 2 September 2008

Keywords: histone deacetylase, inhibitor, combination therapy

Identifiers

Local EPrints ID: 150491

URI: http://eprints.soton.ac.uk/id/eprint/150491

DOI: doi:10.1038/sj.bjc.6604557

ISSN: 0007-0920

PURE UUID: 2cd5f0ef-7ee4-4c2b-82eb-7fa9ebf68270

ORCID for P.W.M. Johnson:

orcid.org/0000-0003-2306-4974

ORCID for G. Packham:

orcid.org/0000-0002-9232-5691

ORCID for S.J. Crabb:

orcid.org/0000-0003-3521-9064

Catalogue record

Date deposited: 05 May 2010 13:41

Last modified: 14 Mar 2024 02:48

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Contributors

Author: L. Nolan

Author: P.W.M. Johnson

Author: A. Ganesan

Author: G. Packham

Author: S.J. Crabb

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