Developmental dysplasia of the hip and occult neurology
Luther, Alison Z. and Clarke, Nicholas M. (2008) Developmental dysplasia of the hip and occult neurology. Clinical Orthopaedics and Related Research, 466, (4), 871-877. (doi:10.1007/s11999-008-0118-6.).
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Developmental dysplasia of the hip (DDH) is a neonatal condition with various causes. Neuromuscular dysplasia of the hip (NDH) is a sequel of neuromuscular disease, and generally presents later in childhood than DDH. Some evidence, however, supports a concept of a neuromuscular etiology of DDH: (1) a high prevalence of spinal dysraphism in DDH; and (2) abnormal sensory evoked potentials in 31% of DDH patients.
To explore this suggestion we ascertained the presence of neuromuscular disease within a cohort of DDH patients, and asked whether the neuromuscular condition is the initial etiology of the dysplasia or a coincidental finding. We retrospectively reviewed patients presenting with DDH. Only those with an initial diagnosis of DDH and a subsequent diagnosis of a neuromuscular condition were assessed. Fifteen of 560 patients fulfilled the criteria, however the presence of true DDH within this group was minimal, as several cases emerged as early presenting NDH.
We therefore believe it unlikely DDH has a substantial neurological etiology.
Level of evidence:
Level III, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.
|Subjects:||R Medicine > R Medicine (General)|
|Divisions:||University Structure - Pre August 2011 > School of Medicine > Developmental Origins of Health and Disease
|Date Deposited:||10 May 2010 10:43|
|Last Modified:||02 Mar 2012 13:36|
|Contributors:||Luther, Alison Z. (Author)
Clarke, Nicholas M. (Author)
|RDF:||RDF+N-Triples, RDF+N3, RDF+XML, Browse.|
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