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Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation

Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
Recombinant human growth hormone (somatropin) is currently recommended by NICE1 for children with a proven clinical diagnosis of GHD, TS or PWS and for pre-pubertal children with CRI. Since the last review, somatropin has received marketing authorisation for the treatment of children born SGA and for children with growth failure associated with SHOX deficiency. The review will update and extend the existing systematic review2 with any new evidence for the use of growth hormone for children with GHD, TS, PWS or CRI. In addition, evidence for the use of human growth hormone for children born small for gestational age, or with SHOX deficiency (conditions not considered in the original review) will be included in this report.

The HTA programme commissioned ths technology assessment report on behalf on the National Institute for Health and Clinical Excellence.
1366-5278
Takeda, Andrea
55a013c5-ae02-46c2-b778-93060d250e2d
Cooper, Keith
ea064f58-d71d-404a-bcf3-49d243b8825b
Bird, Alex
a6c30c9f-7730-4782-944e-8f282665e087
Baxter, Louise
c2e955db-6d0e-43c1-8a16-98981727d98e
Gospodarevskaya, Elena
38d92bb3-d2e6-4400-a3f8-513c780fadb2
Frampton, Geoffrey K.
738b9427-87c0-4d1d-a6d2-b3f2d6c35142
Takeda, Andrea
55a013c5-ae02-46c2-b778-93060d250e2d
Cooper, Keith
ea064f58-d71d-404a-bcf3-49d243b8825b
Bird, Alex
a6c30c9f-7730-4782-944e-8f282665e087
Baxter, Louise
c2e955db-6d0e-43c1-8a16-98981727d98e
Gospodarevskaya, Elena
38d92bb3-d2e6-4400-a3f8-513c780fadb2
Frampton, Geoffrey K.
738b9427-87c0-4d1d-a6d2-b3f2d6c35142

Takeda, Andrea, Cooper, Keith, Bird, Alex, Baxter, Louise, Gospodarevskaya, Elena and Frampton, Geoffrey K. (2010) Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation. Health Technology Assessment.

Record type: Article

Abstract

Recombinant human growth hormone (somatropin) is currently recommended by NICE1 for children with a proven clinical diagnosis of GHD, TS or PWS and for pre-pubertal children with CRI. Since the last review, somatropin has received marketing authorisation for the treatment of children born SGA and for children with growth failure associated with SHOX deficiency. The review will update and extend the existing systematic review2 with any new evidence for the use of growth hormone for children with GHD, TS, PWS or CRI. In addition, evidence for the use of human growth hormone for children born small for gestational age, or with SHOX deficiency (conditions not considered in the original review) will be included in this report.

The HTA programme commissioned ths technology assessment report on behalf on the National Institute for Health and Clinical Excellence.

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More information

Published date: August 2010
Additional Information: August 2010. This project is at the editorial review stage. Delays in the review process can cause the forecast publication date to be delayed.

Identifiers

Local EPrints ID: 155449
URI: http://eprints.soton.ac.uk/id/eprint/155449
ISSN: 1366-5278
PURE UUID: f328124a-7b82-4578-9678-ed57bf9432ae
ORCID for Keith Cooper: ORCID iD orcid.org/0000-0002-0318-7670

Catalogue record

Date deposited: 28 May 2010 14:00
Last modified: 18 Mar 2024 02:51

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Contributors

Author: Andrea Takeda
Author: Keith Cooper ORCID iD
Author: Alex Bird
Author: Louise Baxter
Author: Elena Gospodarevskaya
Author: Geoffrey K. Frampton

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