Changes in placental size during Ramadan


Alwasel, S.H., Abotalib, Z., Alijarallah, J.S., Osmond, C., Alkharaz, S.M., Alhazza, I.M., Badr, G. and Barker, D.J.P. (2010) Changes in placental size during Ramadan. Placenta, 31, (7), 607-610. (doi:10.1016/j.placenta.2010.04.010 ).

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Description/Abstract

Background
Placental growth responds to maternal influences. Ramadan is an annual period of day-time fasting during which people in Saudi Arabia, including pregnant women, change their diets and physical activity. Little is known about the effects of this altered lifestyle on placental development.

Methods
We studied the birth records of 7083 babies born over a four-year period to Saudi nationals in Unizah, a small city 350 km to the north of Riyadh, the capital city of Saudi Arabia. The records included birth weight, placental weight and gestational age.

Results
Mean birth weight was similar to European values but the mean placental weight and ratio of placental weight to birth weight were lower. Among babies who were in the second or third trimester of gestation during Ramadan the mean placental weight and ratio were below those of babies who were not in utero during Ramadan. Among boys the mean placental ratios were 14.4 percent (second trimester) and 14.5 percent (third trimester) compared with 14.9 percent (p = <0.001 and 0.002). The corresponding figures for girls were 14.8 and 14.6 percent compared with 15.1 percent (p = 0.02 and <0.001).

Conclusions
In Saudi Arabia placentas respond to mothers’ limited ability to deliver nutrients to them. Placental growth slows but efficiency is increased so that fetal growth is sustained, albeit with a reduced reserve capacity. The lifestyle changes associated with Ramadan further slow placental growth. Ramadan may influence placental growth through dietary changes other than day-time fasting. Changes in placental growth during Ramadan could be associated with altered fetal programming, and may therefore have long-term implications for the health of the next generation.

Item Type: Article
ISSNs: 0143-4004 (print)
1532-3102 (electronic)
Related URLs:
Keywords: placental weight, placental ratio, ramadan, programming
Subjects: H Social Sciences > H Social Sciences (General)
B Philosophy. Psychology. Religion > BP Islam. Bahaism. Theosophy, etc
R Medicine > RG Gynecology and obstetrics
Divisions: University Structure - Pre August 2011 > School of Medicine
ePrint ID: 161219
Date Deposited: 26 Jul 2010 14:04
Last Modified: 27 Mar 2014 19:16
URI: http://eprints.soton.ac.uk/id/eprint/161219

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