Risperidone long-acting injection: a 6-year mirror-image study of healthcare resource use

Taylor, D., Fischetti, C., Sparshatt, A., Thomas, A., Bishara, D. and Cornelius, V. (2009) Risperidone long-acting injection: a 6-year mirror-image study of healthcare resource use. Acta Psychiatrica Scandinavica, 120, (2), 97-101. (doi:10.1111/j.1600-0447.2009.01352.x).


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Objective: To evaluate naturalistic use of risperidone long-acting injection (RLAI) and its effect on healthcare resource use.

Method: Mirror-image comparison of healthcare resource use for 3 years before RLAI initiation and 3 years after.

Results: In total, 211 of 277 patients consecutively prescribed RLAI were evaluable over the full 6-year study period. Median days in hospital/patient increased significantly in the 3 years after RLAI initiation [87 days (inter-quartile range 25–236) before vs. 192 days (47–426) after; P < 0.001]. Those 34 patients who continued RLAI for 3 years showed no change in median bed days [64 days (6.5–182) before vs. 64 days (12–180) after] and median number of admissions was decreased [1.5 (1–2.25) before vs. 1.00 (0–1.25) after; P = 0.001]. Healthcare costs more than doubled for the whole cohort (P < 0.001) and discontinuers (P < 0.001) and increased significantly for continuers (P = 0.010).

Conclusion:? RLAI did not decrease either time spent in hospital or overall healthcare costs in this patient cohort.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1111/j.1600-0447.2009.01352.x
ISSNs: 0001-690X (print)
1600-0447 (electronic)
Related URLs:
Keywords: risperidone, bed stay, healthcare resource, antipsychotics
Subjects: R Medicine > RB Pathology
R Medicine > RM Therapeutics. Pharmacology
Divisions : University Structure - Pre August 2011 > School of Medicine > Community Clinical Sciences
ePrint ID: 162017
Accepted Date and Publication Date:
5 February 2009Published
Date Deposited: 12 Aug 2010 10:32
Last Modified: 31 Mar 2016 13:28
URI: http://eprints.soton.ac.uk/id/eprint/162017

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