Rapid prototyping of ceramic lattices for hard tissue scaffolds
Rapid prototyping of ceramic lattices for hard tissue scaffolds
Hard tissue engineering scaffolds were prepared by micro-extrusion freeforming using biphase calcium phosphate powders. This technique allows both the shape and a hierarchical pore structure within the shape to be designed on the computer and promptly downloaded onto a three-axis building platform. We report on the implementation of six types of design in which the systematic exploration of different void structures can be achieved using one sample configuration. In this way, void sizes from 50 ?m to 500 ?m are built into a lattice such that histological studies can deliver the maximum information from the minimum of testing. This technique also allows multi-scale hierarchies of void structure to be built into one component such that large voids intended for vascularisation can accompany smaller recesses which can host osteoblast development as well as conferring mechanical strength.
extrusion, engineering ceramics, fibres and fluids
1802-1809
Yang, Shoufeng
e0018adf-8123-4a54-b8dd-306c10ca48f1
Yang, Hongyi
288e5171-b749-4591-b1a5-ed8fa99382a3
Chi, Xiaopeng
b1e976e2-a813-4dfe-9cf9-eb0619c90372
Evans, Julian R.G.
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Thompson, Ian
b6921c31-3afa-46bd-8991-ab55f9469027
Cook, Richard J.
9b1649e4-3334-486f-9f9c-1992401b6c8c
Robinson, Paul
5723a86b-7a96-4991-a60c-a2a25ed0781f
October 2008
Yang, Shoufeng
e0018adf-8123-4a54-b8dd-306c10ca48f1
Yang, Hongyi
288e5171-b749-4591-b1a5-ed8fa99382a3
Chi, Xiaopeng
b1e976e2-a813-4dfe-9cf9-eb0619c90372
Evans, Julian R.G.
4eee463a-4dd3-4ef2-b9bc-784246b68ad2
Thompson, Ian
b6921c31-3afa-46bd-8991-ab55f9469027
Cook, Richard J.
9b1649e4-3334-486f-9f9c-1992401b6c8c
Robinson, Paul
5723a86b-7a96-4991-a60c-a2a25ed0781f
Yang, Shoufeng, Yang, Hongyi, Chi, Xiaopeng, Evans, Julian R.G., Thompson, Ian, Cook, Richard J. and Robinson, Paul
(2008)
Rapid prototyping of ceramic lattices for hard tissue scaffolds.
Materials & Design, 29 (9), .
(doi:10.1016/j.matdes.2008.03.024).
Abstract
Hard tissue engineering scaffolds were prepared by micro-extrusion freeforming using biphase calcium phosphate powders. This technique allows both the shape and a hierarchical pore structure within the shape to be designed on the computer and promptly downloaded onto a three-axis building platform. We report on the implementation of six types of design in which the systematic exploration of different void structures can be achieved using one sample configuration. In this way, void sizes from 50 ?m to 500 ?m are built into a lattice such that histological studies can deliver the maximum information from the minimum of testing. This technique also allows multi-scale hierarchies of void structure to be built into one component such that large voids intended for vascularisation can accompany smaller recesses which can host osteoblast development as well as conferring mechanical strength.
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e-pub ahead of print date: 8 April 2008
Published date: October 2008
Keywords:
extrusion, engineering ceramics, fibres and fluids
Organisations:
Engineering Mats & Surface Engineerg Gp
Identifiers
Local EPrints ID: 165037
URI: http://eprints.soton.ac.uk/id/eprint/165037
ISSN: 0261-3069
PURE UUID: 42cb9eff-675a-4ab4-95d6-6b99d94ce33f
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Date deposited: 08 Oct 2010 08:43
Last modified: 14 Mar 2024 02:09
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Contributors
Author:
Hongyi Yang
Author:
Xiaopeng Chi
Author:
Julian R.G. Evans
Author:
Ian Thompson
Author:
Richard J. Cook
Author:
Paul Robinson
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