Microfluidic reactors for controlled synthesis of polymeric micelles
Capretto, Lorenzo, Cheng, Wei, Carugo, Dario, Hill, Martyn and Zhang, Xunli (2010) Microfluidic reactors for controlled synthesis of polymeric micelles. [in special issue: 11th European Sumposium on Controlled Drug Delivery] Journal of Controlled Release, 148, (1), e25-e26. (doi:10.1016/j.jconrel.2010.07.037).
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This study outlines the relationship between polymer concentration, flow rate ratio and microreactor dimension and the size of polymeric micelles produced in continuous flow microreactors. The general production strategy is based on a nanoprecipitation process within the microfluidic environment which improves control, reproducibility, and homogeneity of the size of the produced polymeric micelles.
|Subjects:||R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
|Divisions:||University Structure - Pre August 2011 > School of Engineering Sciences > Bioengineering Sciences
|Date Deposited:||25 Jan 2011 15:01|
|Last Modified:||14 Apr 2014 10:53|
Integrated Synthesis and Characterisation of Organic Nanoparticles Using Microfluidic Technology for Drug Delivery Applications
Funded by: EPSRC (EP/G009732/1)
Led by: Xunli Zhang
27 March 2009 to 26 September 2012
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