Process optimization for the production of alginate microparticles containing wjmscs by a design of experiments (doe) approach
Mazzitelli, S., Capretto, L., Zhang, X.L., Penolazzi, L., Lambertini, E., Piva, R. and Nastruzzi, C. (2010) Process optimization for the production of alginate microparticles containing wjmscs by a design of experiments (doe) approach. [in special issue: 11th European Sumposium on Controlled Drug Delivery] Journal of Controlled Release, 148, (1), e76-e77. (doi:10.1016/j.jconrel.2010.07.014).
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Description/Abstract
The paper describes (a) the isolation and characterization of Wharton's Jelly Mesenchymal Stem cells (WJMSCs), (b) the encapsulation of WJMSCs in alginate microbeads by an encapsulation device based on a vibrating-nozzle, (c) the optimization of the procedure for the encapsulation of WJMSCs by a Design of Experiment (DoE) approach, and (d) the evaluation of viability, proliferation and osteoblastic differentiation of the encapsulated WJMSCs.
| Item Type: | Article |
|---|---|
| ISSNs: | 0168-3659 (print) 1873-4995 (electronic) |
| Subjects: | Q Science > QD Chemistry T Technology > TA Engineering (General). Civil engineering (General) |
| Divisions: | University Structure - Pre August 2011 > School of Engineering Sciences > Bioengineering Sciences |
| Item ID: | 172309 |
| Date Deposited: | 25 Jan 2011 11:52 |
| Last Modified: | 01 Dec 2011 05:49 |
| Contributors: | Mazzitelli, S. (Author) Capretto, L. (Author) Zhang, X.L. (Author) Penolazzi, L. (Author) Lambertini, E. (Author) Piva, R. (Author) Nastruzzi, C. (Author) |
| Date: | 2010 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/172309 |
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