Production of low cost microfluidic chips by a “shrinking” approach: applications to emulsion and microparticle production
Production of low cost microfluidic chips by a “shrinking” approach: applications to emulsion and microparticle production
The present paper describes the production, using a microfluidic approach, of microparticles (constituted of cellulose acetate) and O/W emulsions (constituted of PEG-6 corn oil droplets). The general production strategy is based on the formation of water-in-oil multiphase flow by a focusing mechanism (X-junction chip). The innovative aspect of the work is represented by the fabrication procedure for the microfluidic chip production. The chips were designed and fabricated by a low cost approach using a shrinkable biocompatible polymer
e26-e28
Capretto, L.
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Focaroli, S.
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Zhang, X.L.
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Mazzitelli, S.
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Nastruzzi, C.
10305e34-5e70-461a-9703-deeab9985684
November 2010
Capretto, L.
eef08c1d-b2bf-43f1-a310-39d7405a1f0b
Focaroli, S.
2ca244be-00f6-4e18-8b0b-b4ad3b7d0105
Zhang, X.L.
d7cf1181-3276-4da1-9150-e212b333abb1
Mazzitelli, S.
7ad66607-35de-4950-a089-ad8c53971a93
Nastruzzi, C.
10305e34-5e70-461a-9703-deeab9985684
Capretto, L., Focaroli, S., Zhang, X.L., Mazzitelli, S. and Nastruzzi, C.
(2010)
Production of low cost microfluidic chips by a “shrinking” approach: applications to emulsion and microparticle production.
Journal of Controlled Release, 148 (1), .
(doi:10.1016/j.jconrel.2010.07.038).
Abstract
The present paper describes the production, using a microfluidic approach, of microparticles (constituted of cellulose acetate) and O/W emulsions (constituted of PEG-6 corn oil droplets). The general production strategy is based on the formation of water-in-oil multiphase flow by a focusing mechanism (X-junction chip). The innovative aspect of the work is represented by the fabrication procedure for the microfluidic chip production. The chips were designed and fabricated by a low cost approach using a shrinkable biocompatible polymer
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Published date: November 2010
Additional Information:
11th European Sumposium on Controlled Drug Delivery, editied by Wim Hennink
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Local EPrints ID: 172315
URI: http://eprints.soton.ac.uk/id/eprint/172315
ISSN: 0168-3659
PURE UUID: 560c2378-9f56-46e2-a9a5-e3cc401b8c32
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Date deposited: 26 Jan 2011 08:27
Last modified: 14 Mar 2024 02:52
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Contributors
Author:
L. Capretto
Author:
S. Focaroli
Author:
S. Mazzitelli
Author:
C. Nastruzzi
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