Disseminated intravascular coagulation and purpura fulminans secondary to infection
Faust, S.N., Heyderman, R.S. and Levin, M. (2000) Disseminated intravascular coagulation and purpura fulminans secondary to infection. Best Practice & Research Clinical Haematology, 13, (2), 179-197. (doi:10.1053/beha.2000.0067) (PMID:10942620)
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Description/Abstract
Infection is one of the commonest causes of disseminated intravascular coagulation (DIC). DIC is a complex disorder that results from an imbalance of the pro- and anticoagulant regulatory pathways. This chapter will explain the cellular and molecular basis of the disorder and consider the rationale behind current and experimental treatment strategies.
| Item Type: | Article |
|---|---|
| ISSN: | 1532-1924 (print) |
| Uncontrolled Keywords: | disseminated intravascular coagulation (dic), purpura fulminans; pathophysiology, therapy, clinical trials, gram-negative, meningococcal, tissue factor (tf), tissue factor pathway inhibitor (tfpi), antithrombin (atiii), thrombomodulin (tm), protein c (pc)/activated protein c (apc), tissue plasminogen activator (tpa) |
| Subjects: | Q Science > QR Microbiology > QR180 Immunology Q Science > QR Microbiology > QR355 Virology R Medicine > R Medicine (General) |
| Divisions: | University Structure - Pre August 2011 > School of Medicine > Infection, Inflammation and Repair |
| ePrint ID: | 175585 |
| URI: | http://eprints.soton.ac.uk/id/eprint/175585 |
| Deposited On: | 24 Feb 2011 15:12 |
| Last Modified: | 01 Jun 2011 08:54 |
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