Disseminated intravascular coagulation and purpura fulminans secondary to infection
Disseminated intravascular coagulation and purpura fulminans secondary to infection
Infection is one of the commonest causes of disseminated intravascular coagulation (DIC). DIC is a complex disorder that results from an imbalance of the pro- and anticoagulant regulatory pathways. This chapter will explain the cellular and molecular basis of the disorder and consider the rationale behind current and experimental treatment strategies.
disseminated intravascular coagulation (dic), purpura fulminans, pathophysiology, therapy, clinical trials, gram-negative, meningococcal, tissue factor (tf), tissue factor pathway inhibitor (tfpi), antithrombin (atiii), thrombomodulin (tm), protein c (pc)/activated protein c (apc), tissue plasminogen activator (tpa)
179-197
Faust, S.N.
f97df780-9f9b-418e-b349-7adf63e150c1
Heyderman, R.S.
8f7afe4d-1758-4a08-84a2-fb61f21613ba
Levin, M.
3668029d-82f9-422c-8a69-42ccae2e88bf
June 2000
Faust, S.N.
f97df780-9f9b-418e-b349-7adf63e150c1
Heyderman, R.S.
8f7afe4d-1758-4a08-84a2-fb61f21613ba
Levin, M.
3668029d-82f9-422c-8a69-42ccae2e88bf
Faust, S.N., Heyderman, R.S. and Levin, M.
(2000)
Disseminated intravascular coagulation and purpura fulminans secondary to infection.
Best Practice & Research Clinical Haematology, 13 (2), .
(doi:10.1053/beha.2000.0067).
(PMID:10942620)
Abstract
Infection is one of the commonest causes of disseminated intravascular coagulation (DIC). DIC is a complex disorder that results from an imbalance of the pro- and anticoagulant regulatory pathways. This chapter will explain the cellular and molecular basis of the disorder and consider the rationale behind current and experimental treatment strategies.
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Published date: June 2000
Keywords:
disseminated intravascular coagulation (dic), purpura fulminans, pathophysiology, therapy, clinical trials, gram-negative, meningococcal, tissue factor (tf), tissue factor pathway inhibitor (tfpi), antithrombin (atiii), thrombomodulin (tm), protein c (pc)/activated protein c (apc), tissue plasminogen activator (tpa)
Identifiers
Local EPrints ID: 175585
URI: http://eprints.soton.ac.uk/id/eprint/175585
ISSN: 1532-1924
PURE UUID: 182ed328-2ac7-413f-9f5b-19ae27a8e7a7
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Date deposited: 24 Feb 2011 15:12
Last modified: 14 Mar 2024 02:51
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Author:
R.S. Heyderman
Author:
M. Levin
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