Disseminated intravascular coagulation and purpura fulminans secondary to infection


Faust, S.N., Heyderman, R.S. and Levin, M. (2000) Disseminated intravascular coagulation and purpura fulminans secondary to infection. Best Practice & Research Clinical Haematology, 13, (2), 179-197. (doi:10.1053/beha.2000.0067). (PMID:10942620).

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Description/Abstract

Infection is one of the commonest causes of disseminated intravascular coagulation (DIC). DIC is a complex disorder that results from an imbalance of the pro- and anticoagulant regulatory pathways. This chapter will explain the cellular and molecular basis of the disorder and consider the rationale behind current and experimental treatment strategies.

Item Type: Article
ISSNs: 1532-1924 (print)
Keywords: disseminated intravascular coagulation (dic), purpura fulminans; pathophysiology, therapy, clinical trials, gram-negative, meningococcal, tissue factor (tf), tissue factor pathway inhibitor (tfpi), antithrombin (atiii), thrombomodulin (tm), protein c (pc)/activated protein c (apc), tissue plasminogen activator (tpa)
Subjects: Q Science > QR Microbiology > QR180 Immunology
Q Science > QR Microbiology > QR355 Virology
R Medicine > R Medicine (General)
Divisions: University Structure - Pre August 2011 > School of Medicine > Infection, Inflammation and Repair
ePrint ID: 175585
Date Deposited: 24 Feb 2011 15:12
Last Modified: 27 Mar 2014 19:21
URI: http://eprints.soton.ac.uk/id/eprint/175585

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