Development of a questionnaire (EORTC module) to measure quality of life in patients with cholangiocarcinoma and gallbladder cancer, the EORTC QLQ-BIL21
Friend, E., Yadegarfar, G., Byrne, C., Johnson, C.D., Sezer, O., Pucciarelli, S., Pereira, S.P., Chie, W-C., Banfield, A. and Ramage, J.K. (2011) Development of a questionnaire (EORTC module) to measure quality of life in patients with cholangiocarcinoma and gallbladder cancer, the EORTC QLQ-BIL21. British Journal of Cancer, 104, (4), 587-592. (doi:10.1038/sj.bjc.6606086). (PMID:21266979).
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Description/Abstract
Background: Quality of life measurement in cholangiocarcinoma and gallbladder cancer involves the assessment of patient-reported issues related to the symptoms, disease and treatment of these tumours. This study describes the development of the disease-specific quality of life (QoL) questionnaire for patients with cholangiocarcinoma and gallbladder cancer to supplement the European Organization for Research and Treatment of Cancer (EORTC)-QLQ C30 core cancer questionnaire.
Methods: Phases 1–3 of the guidelines for module development published by the EORTC were followed, with adaptations for incorporation of questions from existing modules.
Results: A total of 47 QoL issues (questions) were identified; 44 questions from the two related validated questionnaires, the EORTC QLQ-PAN26 (pancreatic module) and the EORTC QLQ-LMC21 (liver metastases module), two from the Functional Assessment of Cancer Therapy hepatobiliary module questionnaire in the literature search and one from healthcare professional interviews. Following phase 1 and 2 interviews with patients (n=101) and health care professionals (n=6), a 23-question provisional questionnaire was formulated. There were five questions from PAN26, 15 from LMC21 and three extra questions. In phase 3, the provisional item list was pre-tested in 52 patients in four languages and this resulted in a 21-item module.
Conclusion: This is the only disease-specific QoL questionnaire for patients with cholangiocarcinoma and gallbladder cancer, and initial assessments show it to be accurate and acceptable to patients in reflecting QoL in these diseases.
| Item Type: | Article |
|---|---|
| ISSNs: | 0007-0920 (print) 1532-1827 (electronic) |
| Keywords: | cholangiocarcinoma, gall bladder cancer, quality of life |
| Subjects: | H Social Sciences > HM Sociology R Medicine > RA Public aspects of medicine R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
| Divisions: | University Structure - Pre August 2011 > School of Medicine > Cancer Sciences |
| Item ID: | 179319 |
| Date Deposited: | 01 Apr 2011 08:39 |
| Last Modified: | 01 Jun 2011 03:24 |
| Contributors: | Friend, E. (Author) Yadegarfar, G. (Author) Byrne, C. (Author) Johnson, C.D. (Author) Sezer, O. (Author) Pucciarelli, S. (Author) Pereira, S.P. (Author) Chie, W-C. (Author) Banfield, A. (Author) Ramage, J.K. (Author) |
| Date: | 15 February 2011 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/179319 |
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