The University of Southampton
University of Southampton Institutional Repository

A pilot study to inform sample size calculations for an investigation into the effects of electrical stimulation on recovery of hand sensation and function in stroke patients

A pilot study to inform sample size calculations for an investigation into the effects of electrical stimulation on recovery of hand sensation and function in stroke patients
A pilot study to inform sample size calculations for an investigation into the effects of electrical stimulation on recovery of hand sensation and function in stroke patients
Background and Purpose: Recovery of motor function, rather than associated sensory deficits is the main focus of rehabilitation therapy for the upper limb following stroke in the United Kingdom. Sensory deficits are known to have an adverse effect on functional outcome, although their severity is not necessarily related to degree of functional loss. Studies that have included assessment of sensation have proved inconclusive. A retrospective study of stroke patients with restricted hand function and sensation, referred to the authors for electrical stimulation treatment, showed improvement in sensation in the hemiplegic hand in seven out of eleven patients tested measured using static 2 point discrimination of 24 areas of the hand. It is recognised that this previous study had design and methodological limitations. The purpose of this study is to inform sample-size calculations for a full randomised controlled trial to investigate the effects of electrical stimulation on recovery of hand sensation and function in stroke patients.

Methods: 30 subjects, within one year following a first stroke, are randomised into equal treatment and control groups. The treatment group receives electrical stimulation of elbow and wrist extensors and the control group, elbow and wrist extension exercises. Assessments of upper limb function use the Action Research Arm Test and the Jebsen Taylor Hand Function Test. Hand sensation is assessed using Static Two Point Discrimination. Assessments are conducted pre treatment (week 0) mid treatment (week 6) and post treatment (week 12) and 12 weeks post treatment (week 24).

Results: 15 subjects (9 female, 6 male) have so far been recruited to the study, (mean age) between 2 months and 1 year after stroke. Of these one has completed the study and six others have completed the treatment period only. Further results will be presented.
stroke
1858991560
214 - 217
Bournemouth University
Mann, G.E.
1610a1ba-7f18-4a66-9966-69e5e7a3705d
Malone, L.J.
5905dc1d-9ac1-4e3c-a5a1-c9e7b56cde43
Taylor, P.N.
473bd95f-0c3e-443d-b4b7-a929a2c0de21
Burridge, J.H.
c769a50c-6aa9-43f6-9a89-10976d7f9f08
Mann, G.E.
1610a1ba-7f18-4a66-9966-69e5e7a3705d
Malone, L.J.
5905dc1d-9ac1-4e3c-a5a1-c9e7b56cde43
Taylor, P.N.
473bd95f-0c3e-443d-b4b7-a929a2c0de21
Burridge, J.H.
c769a50c-6aa9-43f6-9a89-10976d7f9f08

Mann, G.E., Malone, L.J., Taylor, P.N. and Burridge, J.H. (2001) A pilot study to inform sample size calculations for an investigation into the effects of electrical stimulation on recovery of hand sensation and function in stroke patients. In, 2nd Bournemouth University Academic Biomedical Engineering Research Group Meeting. Salisbury, GB. Bournemouth University, 214 - 217.

Record type: Book Section

Abstract

Background and Purpose: Recovery of motor function, rather than associated sensory deficits is the main focus of rehabilitation therapy for the upper limb following stroke in the United Kingdom. Sensory deficits are known to have an adverse effect on functional outcome, although their severity is not necessarily related to degree of functional loss. Studies that have included assessment of sensation have proved inconclusive. A retrospective study of stroke patients with restricted hand function and sensation, referred to the authors for electrical stimulation treatment, showed improvement in sensation in the hemiplegic hand in seven out of eleven patients tested measured using static 2 point discrimination of 24 areas of the hand. It is recognised that this previous study had design and methodological limitations. The purpose of this study is to inform sample-size calculations for a full randomised controlled trial to investigate the effects of electrical stimulation on recovery of hand sensation and function in stroke patients.

Methods: 30 subjects, within one year following a first stroke, are randomised into equal treatment and control groups. The treatment group receives electrical stimulation of elbow and wrist extensors and the control group, elbow and wrist extension exercises. Assessments of upper limb function use the Action Research Arm Test and the Jebsen Taylor Hand Function Test. Hand sensation is assessed using Static Two Point Discrimination. Assessments are conducted pre treatment (week 0) mid treatment (week 6) and post treatment (week 12) and 12 weeks post treatment (week 24).

Results: 15 subjects (9 female, 6 male) have so far been recruited to the study, (mean age) between 2 months and 1 year after stroke. Of these one has completed the study and six others have completed the treatment period only. Further results will be presented.

This record has no associated files available for download.

More information

Published date: September 2001
Keywords: stroke

Identifiers

Local EPrints ID: 17963
URI: http://eprints.soton.ac.uk/id/eprint/17963
ISBN: 1858991560
PURE UUID: 4f3c4f68-8799-4529-9d91-81b664dc5d0e

Catalogue record

Date deposited: 26 Oct 2005
Last modified: 11 Dec 2021 14:17

Export record

Contributors

Author: G.E. Mann
Author: L.J. Malone
Author: P.N. Taylor
Author: J.H. Burridge

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×