Integrated systems for rapid point of care (PoC) blood cell analysis
van Berkel, Cees, Gwyer, James D., Deane, Steve, Green, Nicolas, Holloway, Judith, Hollis, Veronica and Morgan, Hywel (2011) Integrated systems for rapid point of care (PoC) blood cell analysis. Lab on a Chip - Miniturisation for Chemistry and Biology, 11, (7), 1249-1255. (doi:10.1039/C0LC00587H). (PMID:21331413).
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Description/Abstract
Counting the different subpopulations of cells in a fingerprick of human blood is important for a number of clinical point-of-care (PoC) applications. It is a challenge to demonstrate the integration of sample preparation and detection techniques in a single platform. In this paper we demonstrate a generic microfluidic platform that combines sample processing and characterisation and enumeration in a single, integrated system. Results of microfluidic 3-part differential leukocyte (granulocyte, lymphocyte and monocyte) counts, together with erythrocyte and thrombocyte (platelet) counts, in human blood are shown and corroborated with results from hospital clinical laboratory analysis.
| Item Type: | Article |
|---|---|
| ISSNs: | 1473-0197 (print) 1473-0189 (electronic) |
| Related URLs: | |
| Subjects: | Q Science > QH Natural history > QH301 Biology R Medicine > R Medicine (General) |
| Divisions: | University Structure - Pre August 2011 > School of Electronics and Computer Science University Structure - Pre August 2011 > School of Engineering Sciences University Structure - Pre August 2011 > School of Medicine > Infection, Inflammation and Repair |
| Item ID: | 181025 |
| Date Deposited: | 13 Apr 2011 10:20 |
| Last Modified: | 01 Jun 2011 01:21 |
| Contributors: | van Berkel, Cees (Author) Gwyer, James D. (Author) Deane, Steve (Author) Green, Nicolas (Author) Holloway, Judith (Author) Hollis, Veronica (Author) Morgan, Hywel (Author) |
| Date: | 7 April 2011 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/181025 |
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