The University of Southampton
University of Southampton Institutional Repository

Evaluating the clonal hierarchy in light-chain multiple myeloma: implications against the myeloma stem cell hypothesis

Evaluating the clonal hierarchy in light-chain multiple myeloma: implications against the myeloma stem cell hypothesis
Evaluating the clonal hierarchy in light-chain multiple myeloma: implications against the myeloma stem cell hypothesis
An exclusive production of light chains can be found in ~15% of myeloma cases, and in these light-chain multiple myeloma (LC-MM) cases, the phenotype remains unchanged throughout subsequent progression and relapse. Once established, it suggests that this phenotype is maintained by the ‘feeder cell’ that re-populates the tumor bulk as disease re-emerges

0887-6924
1213-1216
Pfeifer, Sabine
f3c9d927-7ee7-4233-bdb8-c8bab8e3962d
Perez-Andres, Martin
2af73e7b-7918-400b-9687-70a83a48bc31
Ludwig, Heinz
e1ea5005-de05-4940-a14c-4f1c8f54def9
Sahota, Surinder S.
66c1457f-cba2-4c49-9c8c-fcee0748b6b8
Zojer, Niklas
88a51a4d-0b56-4832-bc0f-f102fc49d656
Pfeifer, Sabine
f3c9d927-7ee7-4233-bdb8-c8bab8e3962d
Perez-Andres, Martin
2af73e7b-7918-400b-9687-70a83a48bc31
Ludwig, Heinz
e1ea5005-de05-4940-a14c-4f1c8f54def9
Sahota, Surinder S.
66c1457f-cba2-4c49-9c8c-fcee0748b6b8
Zojer, Niklas
88a51a4d-0b56-4832-bc0f-f102fc49d656

Pfeifer, Sabine, Perez-Andres, Martin, Ludwig, Heinz, Sahota, Surinder S. and Zojer, Niklas (2011) Evaluating the clonal hierarchy in light-chain multiple myeloma: implications against the myeloma stem cell hypothesis. Leukemia, 25, 1213-1216. (doi:10.1038/leu.2011.70). (PMID:21494259)

Record type: Article

Abstract

An exclusive production of light chains can be found in ~15% of myeloma cases, and in these light-chain multiple myeloma (LC-MM) cases, the phenotype remains unchanged throughout subsequent progression and relapse. Once established, it suggests that this phenotype is maintained by the ‘feeder cell’ that re-populates the tumor bulk as disease re-emerges

This record has no associated files available for download.

More information

Published date: 15 April 2011
Organisations: Faculty of Medicine, Cancer Sciences

Identifiers

Local EPrints ID: 181785
URI: http://eprints.soton.ac.uk/id/eprint/181785
ISSN: 0887-6924
PURE UUID: 05ebbc93-03a4-4917-a6c1-6263860765ac

Catalogue record

Date deposited: 19 Apr 2011 14:11
Last modified: 14 Mar 2024 02:57

Export record

Altmetrics

Contributors

Author: Sabine Pfeifer
Author: Martin Perez-Andres
Author: Heinz Ludwig
Author: Surinder S. Sahota
Author: Niklas Zojer

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×