Increased preconception omega-3 polyunsaturated fatty acid intake improves embryo morphology
Increased preconception omega-3 polyunsaturated fatty acid intake improves embryo morphology
The association between preconception dietary intake of the polyunsaturated fatty acids (LC-PUFAs) omega-6 and omega-3 and the E(2) levels and IVF/intracytoplasmic sperm injection (ICSI) outcome were investigated in women in a prospective study. It revealed that high intakes of omega-3 LC-PUFA alpha-linolenic acid increase baseline E(2), high intakes of eicosapentaenoic acid and docosahexaenoic acid reduce E(2) response and the number of follicles after ovarian stimulation, and total omega-3 intake, in particular alpha-linolenic acid and docosahexaenoic acid, improve embryo morphology.
nutrition, assisted reproduction, fertility outcome
1820-1823
Hammiche, Fatima
918ca043-2fb2-47fe-a40b-97edd82785ed
Vujkovic, Marijana
428e3172-91f8-4c66-a9be-8bd0f688dce9
Wilburg, Willeke
dfa809fd-c8f3-4165-a067-44fb29d5f63d
de Vries, Jeanne H.M.
ed595365-aafa-4ec4-b43d-e190ac06834f
Macklon, Nick S.
7db1f4fc-a9f6-431f-a1f2-297bb8c9fb7e
Laven, Joop S.E.
840def1a-6693-4488-b412-29794c5fc56f
Steegers-Theunissen, Régine P.M.
804e3a09-9001-4b36-936c-e3ea5b856750
April 2011
Hammiche, Fatima
918ca043-2fb2-47fe-a40b-97edd82785ed
Vujkovic, Marijana
428e3172-91f8-4c66-a9be-8bd0f688dce9
Wilburg, Willeke
dfa809fd-c8f3-4165-a067-44fb29d5f63d
de Vries, Jeanne H.M.
ed595365-aafa-4ec4-b43d-e190ac06834f
Macklon, Nick S.
7db1f4fc-a9f6-431f-a1f2-297bb8c9fb7e
Laven, Joop S.E.
840def1a-6693-4488-b412-29794c5fc56f
Steegers-Theunissen, Régine P.M.
804e3a09-9001-4b36-936c-e3ea5b856750
Hammiche, Fatima, Vujkovic, Marijana, Wilburg, Willeke, de Vries, Jeanne H.M., Macklon, Nick S., Laven, Joop S.E. and Steegers-Theunissen, Régine P.M.
(2011)
Increased preconception omega-3 polyunsaturated fatty acid intake improves embryo morphology.
Fertility and Sterility, 95 (5), .
(doi:10.1016/j.fertnstert.2010.11.021).
(PMID:21130435)
Abstract
The association between preconception dietary intake of the polyunsaturated fatty acids (LC-PUFAs) omega-6 and omega-3 and the E(2) levels and IVF/intracytoplasmic sperm injection (ICSI) outcome were investigated in women in a prospective study. It revealed that high intakes of omega-3 LC-PUFA alpha-linolenic acid increase baseline E(2), high intakes of eicosapentaenoic acid and docosahexaenoic acid reduce E(2) response and the number of follicles after ovarian stimulation, and total omega-3 intake, in particular alpha-linolenic acid and docosahexaenoic acid, improve embryo morphology.
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Published date: April 2011
Keywords:
nutrition, assisted reproduction, fertility outcome
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Local EPrints ID: 185235
URI: http://eprints.soton.ac.uk/id/eprint/185235
ISSN: 0015-0282
PURE UUID: 9b211b63-504b-4f3f-8285-0bf91d109de1
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Date deposited: 10 May 2011 08:37
Last modified: 14 Mar 2024 03:12
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Contributors
Author:
Fatima Hammiche
Author:
Marijana Vujkovic
Author:
Willeke Wilburg
Author:
Jeanne H.M. de Vries
Author:
Nick S. Macklon
Author:
Joop S.E. Laven
Author:
Régine P.M. Steegers-Theunissen
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