Increased preconception omega-3 polyunsaturated fatty acid intake improves embryo morphology
Hammiche, Fatima, Vujkovic, Marijana, Wilburg, Willeke, de Vries, Jeanne H.M., Macklon, Nick S., Laven, Joop S.E. and Steegers-Theunissen, Régine P.M. (2011) Increased preconception omega-3 polyunsaturated fatty acid intake improves embryo morphology. Fertility and Sterility, 95, (5), 1820-1823. (doi:10.1016/j.fertnstert.2010.11.021 ). (PMID:21130435).
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Description/Abstract
The association between preconception dietary intake of the polyunsaturated fatty acids (LC-PUFAs) omega-6 and omega-3 and the E(2) levels and IVF/intracytoplasmic sperm injection (ICSI) outcome were investigated in women in a prospective study. It revealed that high intakes of omega-3 LC-PUFA alpha-linolenic acid increase baseline E(2), high intakes of eicosapentaenoic acid and docosahexaenoic acid reduce E(2) response and the number of follicles after ovarian stimulation, and total omega-3 intake, in particular alpha-linolenic acid and docosahexaenoic acid, improve embryo morphology.
| Item Type: | Article |
|---|---|
| ISSNs: | 0015-0282 (print) |
| Keywords: | nutrition, assisted reproduction, fertility outcome |
| Subjects: | R Medicine > RG Gynecology and obstetrics |
| Divisions: | University Structure - Pre August 2011 > School of Medicine > Developmental Origins of Health and Disease |
| Item ID: | 185235 |
| Date Deposited: | 10 May 2011 08:37 |
| Last Modified: | 01 Jun 2011 10:30 |
| Contributors: | Hammiche, Fatima (Author) Vujkovic, Marijana (Author) Wilburg, Willeke (Author) de Vries, Jeanne H.M. (Author) Macklon, Nick S. (Author) Laven, Joop S.E. (Author) Steegers-Theunissen, Régine P.M. (Author) |
| Date: | April 2011 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/185235 |
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