FSH response-dose can be predicted in ovulation induction for normogonadotropic anovulatory infertility
van Santbrink, E.J., Eijkemans, M.J., Macklon, N.S. and Fauser, B.C. (2002) FSH response-dose can be predicted in ovulation induction for normogonadotropic anovulatory infertility. European Journal of Endocrinology, 147, (2), 223-226. (doi:10.1530/eje.0.1470223). (PMID:12153744).
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The patient group with the best step-down profile for ovulation induction exhibited the closest match between the clinically applied and calculated starting dose of gonadotropins. Therefore, this study provides support for the concept that the individual effective FSH starting dose for gonadotropin induction of ovulation in anovulatory infertile patients can be predicted on the basis of initial screening characteristics, such as body mass index, clomiphene resistance or failure, free IGF-I and FSH. This may result in more effective patient treatment protocols, reduced complication rates and health-economic benefits.
|Digital Object Identifier (DOI):||doi:10.1530/eje.0.1470223|
|Keywords:||treatment protocols, reduced complication rates and health-economic benefits|
|Subjects:||R Medicine > RG Gynecology and obstetrics
R Medicine > RM Therapeutics. Pharmacology
|Divisions:||University Structure - Pre August 2011 > School of Medicine > Developmental Origins of Health and Disease
|Date Deposited:||19 May 2011 09:10|
|Last Modified:||31 Mar 2016 13:38|
|RDF:||RDF+N-Triples, RDF+N3, RDF+XML, Browse.|
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