Dissociation of wanting and liking for alcohol in humans: a test of the incentive-sensitisation theory
Hobbs, Malcolm, Remington, Bob and Glautier, Steven (2005) Dissociation of wanting and liking for alcohol in humans: a test of the incentive-sensitisation theory. Psychopharmacology, 178, (4), 493-499. (doi:10.1007/s00213-004-2026-0)
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Official URL: http://dx.doi.org/10.1007/s00213-004-2026-0
Description/Abstract
Rationale: incentive sensitisation theory (IST) claims that the mechanism of reward is comprised of separate neurobiological systems of wanting and liking, that dependent drug use occurs as a result of sensitisation of the system controlling wanting, and that the two systems can be dissociated.
Objective: to test the IST prediction that wanting and liking for alcohol can be dissociated in humans.
Methods: measures of wanting and liking for alcohol were obtained in three experiments. Experiment 1 examined whether liking for alcohol was associated with levels of wanting, as indexed by self-reported weekly alcohol intake. Experiments 2 and 3 also assessed the association between liking and wanting but in these experiments wanting was also indexed by alcohol consumption in the laboratory. Experiment 2 increased wanting for alcohol using an alcohol priming dose to determine whether liking would be similarly affected. Experiment 3 reduced liking for alcohol by adulterating drinks with Tween to see whether wanting would also be reduced.
Results: little evidence for an association between liking and wanting for alcohol was found in Experiments 1–3 but, collapsing across all experiments, a weak positive correlation between liking and wanting was found. However, in Experiment 2, wanting was increased by the alcohol priming dose whereas liking was not and in Experiment 3 liking was reduced without a concurrent reduction in wanting.
Conclusions: although correlations between wanting and liking can be observed these results support the contention of the IST that wanting and liking for alcohol can be dissociated in human participants.
| Item Type: | Article |
|---|---|
| ISSN: | 0033-3158 (print) |
| Uncontrolled Keywords: | incentive sensitisation theory, wanting, liking, alcohol, dissociation, addiction |
| Related URLs: | http://www.ncbi.nlm.nih.gov/en...query_hl=2 http://dx.doi.org/10.1007/s002...004-2026-0 |
| Subjects: | R Medicine > RM Therapeutics. Pharmacology B Philosophy. Psychology. Religion > BF Psychology |
| Divisions: | University Structure - Pre August 2011 > School of Psychology > Division of Human Wellbeing University Structure - Pre August 2011 > School of Psychology > Division of Cognition |
| ePrint ID: | 18600 |
| URI: | http://eprints.soton.ac.uk/id/eprint/18600 |
| Deposited On: | 01 Dec 2005 |
| Last Modified: | 01 Jun 2011 09:31 |
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