Management of anti-Rhesus-D antibodies in pregnancy: a review from 1994 to 1998
Cheong, Ying C., Goodrick, Jean, Kyle, Phillippa M. and Soothill, Peter (2001) Management of anti-Rhesus-D antibodies in pregnancy: a review from 1994 to 1998. Fetal Diagnosis and Therapy, 16, (5), 294-298. (doi:10.1159/000053931). (PMID:11509852).
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Intravascular as opposed to intraperitoneal transfusions were found to be the main method of transfusion in the later years in this study, a finding which was expected with improved sonographic equipment. Apart from this, management and prognosis of anti-D red cell isoimmunisation in pregnancy have remained relatively stable since the 1980s. Amniocentesis was useful in the management of such pregnancies, especially as an initial procedure in the cases with a lower initial anti-D level. In this series 90% of the fetuses requiring blood transfusion, but were without hydrops, survived, whereas this was about 70%, if they had become hydropic (this latter figure was reduced by 2 hydropic deaths before 20 weeks' gestation in the same very severely affected woman).
|Digital Object Identifier (DOI):||doi:10.1159/000053931|
|Keywords:||rhesus disease, fetal transfusion, anti-a|
|Subjects:||Q Science > QR Microbiology > QR180 Immunology
R Medicine > RB Pathology
R Medicine > RG Gynecology and obstetrics
|Divisions:||University Structure - Pre August 2011 > School of Medicine > Developmental Origins of Health and Disease
|Date Deposited:||20 May 2011 13:10|
|Last Modified:||27 Mar 2014 19:41|
|RDF:||RDF+N-Triples, RDF+N3, RDF+XML, Browse.|
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