The University of Southampton
University of Southampton Institutional Repository

Controversies in the management of ectopic pregnancy

Controversies in the management of ectopic pregnancy
Controversies in the management of ectopic pregnancy
Ectopic pregnancy is a common clinical problem, but there appears to be much controversy surrounding the surgical management of its occurence. This paper reviews the available evidence on the management of ectopic pregnancy. The discussion focuses initially around the choice of medical versus surgical treatment. Next, the question is addressed that if surgical management is deemed necessary, whether the approach should be laparoscopic or via open laparotomy. Lastly, if surgery is undertaken, should salpingectomy or salpingotomy be performed? Laparoscopy will remain the main method of treatment for women with ectopic pregnancy, as it provides obvious advantages over open surgery. On balance, salpingotomy should be the surgical treatment of choice for the majority of women with ectopic pregnancy, as it results in a higher subsequent pregnancy rate, although there is a slightly higher recurrent ectopic pregnancy rate and persistent trophoblastic disease rate when compared with women treated with salpingectomy. There is also a place for medical treatment of women with low concentrations of human chorionic gonadotrophin. A variable dosing methotrexate regimen is more effective compared with single dose regimen, and the fixed multiple regimen is associated with a high rate of side effects.
1472-6483
396-402
Cheong, Ying
4efbba2a-3036-4dce-82f1-8b4017952c83
Li, T.C.
e5ba5bf8-481f-4879-9741-45e75333fea0
Cheong, Ying
4efbba2a-3036-4dce-82f1-8b4017952c83
Li, T.C.
e5ba5bf8-481f-4879-9741-45e75333fea0

Cheong, Ying and Li, T.C. (2007) Controversies in the management of ectopic pregnancy. Reproductive BioMedicine Online, 15 (4), 396-402. (doi:10.1016/S1472-6483(10)60364-1). (PMID:17908401)

Record type: Article

Abstract

Ectopic pregnancy is a common clinical problem, but there appears to be much controversy surrounding the surgical management of its occurence. This paper reviews the available evidence on the management of ectopic pregnancy. The discussion focuses initially around the choice of medical versus surgical treatment. Next, the question is addressed that if surgical management is deemed necessary, whether the approach should be laparoscopic or via open laparotomy. Lastly, if surgery is undertaken, should salpingectomy or salpingotomy be performed? Laparoscopy will remain the main method of treatment for women with ectopic pregnancy, as it provides obvious advantages over open surgery. On balance, salpingotomy should be the surgical treatment of choice for the majority of women with ectopic pregnancy, as it results in a higher subsequent pregnancy rate, although there is a slightly higher recurrent ectopic pregnancy rate and persistent trophoblastic disease rate when compared with women treated with salpingectomy. There is also a place for medical treatment of women with low concentrations of human chorionic gonadotrophin. A variable dosing methotrexate regimen is more effective compared with single dose regimen, and the fixed multiple regimen is associated with a high rate of side effects.

This record has no associated files available for download.

More information

Published date: October 2007

Identifiers

Local EPrints ID: 187885
URI: http://eprints.soton.ac.uk/id/eprint/187885
ISSN: 1472-6483
PURE UUID: 831eebbe-3d56-475d-8b70-1d71151cdef8
ORCID for Ying Cheong: ORCID iD orcid.org/0000-0001-7687-4597

Catalogue record

Date deposited: 19 May 2011 07:54
Last modified: 15 Mar 2024 03:30

Export record

Altmetrics

Contributors

Author: Ying Cheong ORCID iD
Author: T.C. Li

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×