Solid-phase synthesis of cyclic sulfonamides employing a ring-closing metathesis-cleavage strategy
Brown, R. C. D., Castro, J. L. and Moriggi, J. D. (2000) Solid-phase synthesis of cyclic sulfonamides employing a ring-closing metathesis-cleavage strategy. Tetrahedron Letters, 41, (19), 3681-3685. (doi:10.1016/S0040-4039(00)00442-1).
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Original Publication URL: http://dx.doi.org/10.1016/S0040-4039(00)00442-1
Description/Abstract
Ring-closing olefin metathesis using the Grubbs catalyst was applied to the cyclisative release of resin-bound sulfonamides. Flexible linkers apparently facilitated the cyclisation-leavage, allowing a number of novel cyclic sulfonamides to be prepared in good yields using catalytic amounts of the Grubbs catalyst.
| Item Type: | Article |
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| Related URLs: | |
| Keywords: | ring-closing metathesis, solid-phase synthesis, sulfonamides, linkers organic-synthesis, olefin metathesis, support, oligosaccharides, heterocycles, cyclization |
| Subjects: | Q Science Q Science > QD Chemistry |
| Divisions: | University Structure - Pre August 2011 > School of Chemistry |
| Item ID: | 18909 |
| Date Deposited: | 15 Dec 2005 |
| Last Modified: | 01 Jun 2011 03:54 |
| Contributors: | Brown, R. C. D. (Author) Castro, J. L. (Author) Moriggi, J. D. (Author) |
| Date: | 6 May 2000 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/18909 |
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