A selenide linker for "traceless" solid-phase organic synthesis
Li, Z. G., Kulkarni, B. A. and Ganesan, A. (2000) A selenide linker for "traceless" solid-phase organic synthesis. Biotechnology and Bioengineering, 71, (2), 104-106. (doi: 10.1002/1097-0290(2000)71:2<104::AID-BIT1000>3.0.CO;2-7).
Download
Full text not available from this repository.
Original Publication URL: http://www3.interscience.wiley.com/cgi-bin/abstrac...
Description/Abstract
4-Bromophenethyl alcohol was protected as the THP ether, followed by reaction with magnesium and selenium to give the corresponding diselenide. Ether deprotection provides a diselenide diol, which is attached to solid-phase resins. The polymer-bound selenide anion is then generated, and functions as a traceless linker for electrophiles such as alkyl halides.
| Item Type: | Article |
|---|---|
| Related URLs: | |
| Keywords: | solid-phase synthesis, traceless linkers, selenides strategies, cleavage |
| Subjects: | Q Science Q Science > QD Chemistry |
| Divisions: | University Structure - Pre August 2011 > School of Chemistry |
| Item ID: | 18917 |
| Date Deposited: | 18 Jan 2006 |
| Last Modified: | 01 Jun 2011 13:34 |
| Contributors: | Li, Z. G. (Author) Kulkarni, B. A. (Author) Ganesan, A. (Author) |
| Date: | 2000 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/18917 |
Actions (login required)
 |
View Item |
