Bilateral spastic cerebral palsy--MRI pathology and origin. Analysis from a representative series of 56 cases.
Krägeloh-Mann, Ingeborg, Petersen, Dirk, Hagberg, Gudrun, Vollmer, Brigitte, Hagberg, Bengt and Michaelis, Richard (1995) Bilateral spastic cerebral palsy--MRI pathology and origin. Analysis from a representative series of 56 cases. Developmental Medicine & Child Neurology, 37, (5), 379-397. (doi:10.1111/j.1469-8749.1995.tb12022.x). (PMID:8566452).
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Description/Abstract
MRI of the brain was performed on 56 children with bilateral spastic cerebral palsy (CP) at a mean age of 10.7 years. Specific pathology was found in 91 per cent; periventricular leukomalacia was present in 42 per cent of term- and 87 per cent of preterm-born children. Parasagittal subcorticocortical injury, multicystic encephalomalacia and basal ganglia lesions were identified in 16 per cent, in all but one associated with severe peri-/neonatal events at term or near term. Maldevelopment comprised 9 per cent, all but one found in term-born children. MRI morphology correlated strikingly with outcome. Periventricular leukomalacia was associated with more severe disability in term- than preterm-born children.
| Item Type: | Article |
|---|---|
| ISSNs: | 0012-1622 (print) 1469-8749 (electronic) |
| Subjects: | R Medicine > RB Pathology R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry R Medicine > RJ Pediatrics |
| Divisions: | University Structure - Pre August 2011 > School of Medicine > Clinical Neurosciences |
| Item ID: | 189533 |
| Date Deposited: | 02 Jun 2011 15:27 |
| Last Modified: | 02 Mar 2012 11:37 |
| Contributors: | Krägeloh-Mann, Ingeborg (Author) Petersen, Dirk (Author) Hagberg, Gudrun (Author) Vollmer, Brigitte (Author) Hagberg, Bengt (Author) Michaelis, Richard (Author) |
| Date: | May 1995 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/189533 |
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