Cardiovascular effects of marine omega-3 fatty acids
Cardiovascular effects of marine omega-3 fatty acids
Much evidence shows that the marine omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid have beneficial effects in various cardiac disorders, and their use is recommended in guidelines for management of patients after myocardial infarction. However, questions have been raised about their usefulness alongside optimum medical therapies with agents proven to reduce risk of cardiac events in high-risk patients. Additionally, there is some evidence for a possible pro-arrhythmic effect in subsets of cardiac patients. Some uncertainly exists about the optimum dose needed to obtain beneficial effects and the relative merit of dietary intake of omega-3 polyunsaturated fatty acids versus supplements. We review evidence for the effects of omega-3 polyunsaturated fatty acids on various cardiac disorders and the risk factors for cardiac disease. We also assess areas of uncertainty needing further research
540-550
Saravan, Palaniappan
aa25590d-8dd3-47eb-9a15-ed358e55587c
Davidson, Neil C.
31a26738-1c66-424f-bad1-7314d3f50a2b
Schmidt, Erik B.
8b5644dc-de8b-408a-a28b-41ed39ca78c2
Calder, Philip C.
1797e54f-378e-4dcb-80a4-3e30018f07a6
August 2010
Saravan, Palaniappan
aa25590d-8dd3-47eb-9a15-ed358e55587c
Davidson, Neil C.
31a26738-1c66-424f-bad1-7314d3f50a2b
Schmidt, Erik B.
8b5644dc-de8b-408a-a28b-41ed39ca78c2
Calder, Philip C.
1797e54f-378e-4dcb-80a4-3e30018f07a6
Abstract
Much evidence shows that the marine omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid have beneficial effects in various cardiac disorders, and their use is recommended in guidelines for management of patients after myocardial infarction. However, questions have been raised about their usefulness alongside optimum medical therapies with agents proven to reduce risk of cardiac events in high-risk patients. Additionally, there is some evidence for a possible pro-arrhythmic effect in subsets of cardiac patients. Some uncertainly exists about the optimum dose needed to obtain beneficial effects and the relative merit of dietary intake of omega-3 polyunsaturated fatty acids versus supplements. We review evidence for the effects of omega-3 polyunsaturated fatty acids on various cardiac disorders and the risk factors for cardiac disease. We also assess areas of uncertainty needing further research
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Published date: August 2010
Organisations:
Dev Origins of Health & Disease
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Local EPrints ID: 190145
URI: http://eprints.soton.ac.uk/id/eprint/190145
ISSN: 0140-6736
PURE UUID: 72250835-0f91-4799-8b42-3361bab53e85
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Date deposited: 10 Jun 2011 09:09
Last modified: 15 Mar 2024 02:50
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Author:
Palaniappan Saravan
Author:
Neil C. Davidson
Author:
Erik B. Schmidt
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