Acetoacetoxy ethyl methacrylate (AAEM) resin, a new scavenger for primary amines in the presence of secondary amines
Acetoacetoxy ethyl methacrylate (AAEM) resin, a new scavenger for primary amines in the presence of secondary amines
Preliminary results on a new type of polymer scavenger, acetoacetoxy ethyl methacrylate (AAEM) resin, are reported. AAEM resin can selectively remove primary amines in the presence of secondary amines. Its application in a solution library synthesis is demonstrated.
combinatorial chemistry, reductive alkylation, polymer scavenger, amines
small-molecule libraries, reductive amination, sodiumtriacetoxyborohydride, chemoselective reductions, solution-phase, purification, ketones, aldehydes, borohydride, reagents
8963-8967
Yu, Z. R.
83833cf6-b575-4b4a-a0da-0118a91ff50e
Alesso, S.
ab30f33f-103e-4691-99e5-f37b21201185
Pears, D.
5072fd98-a99e-41a8-9a65-8cc4aaab951a
Worthington, P. A.
44871258-bd15-4224-82ac-5270d6fcd38a
Luke, R. W. A.
c412c683-6064-4ea9-9d0f-07d09b9fea03
Bradley, M.
078a34d6-96c4-4ce1-9aa1-454d9ee0030d
11 November 2000
Yu, Z. R.
83833cf6-b575-4b4a-a0da-0118a91ff50e
Alesso, S.
ab30f33f-103e-4691-99e5-f37b21201185
Pears, D.
5072fd98-a99e-41a8-9a65-8cc4aaab951a
Worthington, P. A.
44871258-bd15-4224-82ac-5270d6fcd38a
Luke, R. W. A.
c412c683-6064-4ea9-9d0f-07d09b9fea03
Bradley, M.
078a34d6-96c4-4ce1-9aa1-454d9ee0030d
Yu, Z. R., Alesso, S., Pears, D., Worthington, P. A., Luke, R. W. A. and Bradley, M.
(2000)
Acetoacetoxy ethyl methacrylate (AAEM) resin, a new scavenger for primary amines in the presence of secondary amines.
Tetrahedron Letters, 41 (46), .
(doi:10.1016/S0040-4039(00)01590-2).
Abstract
Preliminary results on a new type of polymer scavenger, acetoacetoxy ethyl methacrylate (AAEM) resin, are reported. AAEM resin can selectively remove primary amines in the presence of secondary amines. Its application in a solution library synthesis is demonstrated.
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Published date: 11 November 2000
Keywords:
combinatorial chemistry, reductive alkylation, polymer scavenger, amines
small-molecule libraries, reductive amination, sodiumtriacetoxyborohydride, chemoselective reductions, solution-phase, purification, ketones, aldehydes, borohydride, reagents
Identifiers
Local EPrints ID: 19075
URI: http://eprints.soton.ac.uk/id/eprint/19075
ISSN: 0040-4039
PURE UUID: 11046c7b-b997-48f8-ab0c-9e511008ec46
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Date deposited: 15 Dec 2005
Last modified: 15 Mar 2024 06:10
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Contributors
Author:
Z. R. Yu
Author:
S. Alesso
Author:
D. Pears
Author:
P. A. Worthington
Author:
R. W. A. Luke
Author:
M. Bradley
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