Acetoacetoxy ethyl methacrylate (AAEM) resin, a new scavenger for primary amines in the presence of secondary amines


Yu, Z. R., Alesso, S., Pears, D., Worthington, P. A., Luke, R. W. A. and Bradley, M. (2000) Acetoacetoxy ethyl methacrylate (AAEM) resin, a new scavenger for primary amines in the presence of secondary amines. Tetrahedron Letters, 41, (46), 8963-8967. (doi:10.1016/S0040-4039(00)01590-2).

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Description/Abstract

Preliminary results on a new type of polymer scavenger, acetoacetoxy ethyl methacrylate (AAEM) resin, are reported. AAEM resin can selectively remove primary amines in the presence of secondary amines. Its application in a solution library synthesis is demonstrated.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1016/S0040-4039(00)01590-2
Related URLs:
Keywords: combinatorial chemistry, reductive alkylation, polymer scavenger, amines small-molecule libraries, reductive amination, sodiumtriacetoxyborohydride, chemoselective reductions, solution-phase, purification, ketones, aldehydes, borohydride, reagents
Subjects: Q Science
Q Science > QD Chemistry
Divisions : University Structure - Pre August 2011 > School of Chemistry
ePrint ID: 19075
Accepted Date and Publication Date:
Status
11 November 2000Published
Date Deposited: 15 Dec 2005
Last Modified: 31 Mar 2016 11:35
URI: http://eprints.soton.ac.uk/id/eprint/19075

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