Thomson, Nicholas R. and Clarke, Ian N.
Chlamydia trachomatis: small genome, big challenges.
Future Microbiology, 5, (4), . (doi:10.2217/fmb.10.31). (PMID:20353297).
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Chlamydial infections are highly newsworthy, but basic research into Chlamydia trachomatis is severely hampered by a series of formidable technical barriers. This has resulted in a paucity of information with respect to the genetics and population structure of these recalcitrant bacteria. Here we present a review of what is currently known about the genomics of C. trachomatis and discuss the usefulness of molecular typing systems and the prospects of developing a pan-chlamydial genome resource
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