A clinical prediction rule for nerve function impairment in leprosy patients: revisited after 5 years of follow-up


Croft, R.P., Nicholls, P.G., Steyerberg, E.W., Richardus, J.H., Withington, S.G., Cairns, W. and Smith, S. (2003) A clinical prediction rule for nerve function impairment in leprosy patients: revisited after 5 years of follow-up. Leprosy Review, 74, (1), 35-41.

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Description/Abstract

Nerve function impairment (NFI) commonly occurs during or after chemotherapy in leprosy. We previously described a clinical predication rule to estimate the risk of NFI occurring within 2 years of diagnosis, based on 2510 patients who are followed up in the Bangladesh Acute Nerve Damage Study (BANDS). This prediction rule assigns new leprosy patients to one of three risk groups based on leprosy group and the presence or absence of NFI at registration. Updated data with up to 5 years of follow-up showed that 95% of all NFI occurred within 2 years. This study confirms the validity of the rule and supports the conclusion that there is little value for the detection of NFI in extending follow-up beyond 2 years.

Item Type: Article
ISSNs: 0305-7518 (print)
Related URLs:
Keywords: nfi, nerve function impairment, leprosy patients, clinical prediction rule, 5 year follow-up
Subjects: H Social Sciences > HT Communities. Classes. Races
R Medicine > RB Pathology
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: University Structure - Pre August 2011 > Superseded (SONM) > Superseded (LCHN)
ePrint ID: 19208
Date Deposited: 31 Jan 2006
Last Modified: 27 Mar 2014 18:08
URI: http://eprints.soton.ac.uk/id/eprint/19208

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