Solid-phase Friedel-Crafts acylation on polystyrene resins-synthesis of antiepiletic 1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones
Bevacqua, F., Basso, A., Gitto, R., Bradley, M. and Chimirri, A. (2001) Solid-phase Friedel-Crafts acylation on polystyrene resins-synthesis of antiepiletic 1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones. Tetrahedron Letters, 42, (43), 7683-7685. (doi:10.1016/S0040-4039(01)01602-1).
Download
Full text not available from this repository.
Original Publication URL: http://dx.doi.org/10.1016/S0040-4039(01)01602-1
Description/Abstract
Friedel-Crafts acylation with various acyl chlorides of resin-bound 3,4-dimethoxyphenylacetate afforded resin bound ketones which, following treatment with hydrazine, were converted into the corresponding 2,3-benzodiazepines in good yields and purities.
| Item Type: | Article |
|---|---|
| Related URLs: | |
| Keywords: | solid-phase synthesis, friedel-crafts acylation, 2,3-benzodiazepines ampa receptor antagonists |
| Subjects: | Q Science Q Science > QD Chemistry |
| Divisions: | University Structure - Pre August 2011 > School of Chemistry |
| Item ID: | 19406 |
| Date Deposited: | 14 Feb 2006 |
| Last Modified: | 01 Jun 2011 03:56 |
| Contributors: | Bevacqua, F. (Author) Basso, A. (Author) Gitto, R. (Author) Bradley, M. (Author) Chimirri, A. (Author) |
| Date: | 22 October 2001 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/19406 |
Actions (login required)
 |
View Item |
