The University of Southampton
University of Southampton Institutional Repository

Regional differences in treatment for osteoporosis: The global longitudinal study of osteoporosis in women(GLOW)

Regional differences in treatment for osteoporosis: The global longitudinal study of osteoporosis in women(GLOW)
Regional differences in treatment for osteoporosis: The global longitudinal study of osteoporosis in women(GLOW)
Among 58,009 women, current anti-osteoporosis medication use was lowest in Northern Europe (16%) and highest in USA and Australia (32%). Between 48% (USA, Southern Europe) and 68% (Northern Europe) of women aged ? 65 years with a history of spine or hip fracture since age 45 were untreated. Among women with osteoporosis, the percentage of treated cases was lowest in Europe (45–52% versus 62–65% elsewhere). Women with osteopenia and no other risk factors were treated with anti-osteoporosis medication most frequently in USA (31%) and Canada (31%), and least frequently in Southern Europe (12%), Northern Europe (13%), and Australia (16%). After adjusting for risk factors, US women were threefold as likely to be treated with anti-osteoporosis medication as Northern European women (odds ratio 2.8; 95% confidence interval 2.5–3.1) and 1.5 times as likely to be treated as Southern European women (1.5, 1.4–1.6). Up to half of women reporting previous hip or spine fracture did not receive treatment.

fracture, regional variation, women, risk factor, preventive treatment
8756-3282
493-498
Diez-Perez, Adolfo
19f89c53-003a-469c-92ac-69b0b979f3ec
Hooven, Frederick H.
75487234-9de4-4d47-a837-b72662e751ea
Adachi, Jonathan D.
b332030f-9df9-4fb8-8547-7192a37b2522
Adami, Silvano
cc35505b-b752-4ce0-a246-17e1de60a174
Anderson, Frederick A.
46c5965f-b6d7-4682-8435-ec8b085d2ed9
Boonen, Steven
fbfd999d-e425-406c-b66e-ca1b8150497b
Chapurlat, Roland
d9410f8c-4e4a-465b-8fb6-67efaadaad4c
Compston, Juliet E.
1038f0cb-dd36-49e5-8609-9091266faf67
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Delmas, Pierre
818c03cd-1ef6-4bf8-a5d2-9b4aa5019d98
Greenspan, Susan L.
bca80638-bd85-4682-8012-037c880dfd06
Lacroix, Andrea Z.
cd86dbf8-3782-4f89-a9d1-0d44f2a39b0a
Lindsay, Robert
9508787f-a0b6-4155-95f7-33c57e4f56a0
Netelenbos, J. Coen
9dbd9f31-46f9-4386-a2c9-8826897e652c
Pfeilschifter, Johannes
668ca581-77d4-4cfd-8621-ce542183b90e
Roux, Christian
1f852839-8036-423f-ade1-a003d42271fa
Saag, Kenneth G.
c9b4325d-9687-48a3-9985-0c7587650f31
Sambrook, Philip
2f7848ec-18b4-4bdd-9a9b-a9a767bf31b7
Silverman, Stuart
b3ed983a-c9f6-4029-babe-d5d9dce72375
Siris, Ethel S.
cc6622ff-fdce-4834-8edf-b9229094f755
Watts, Nelson B.
5c0d14e9-020d-4e1f-802a-163636c5f0ea
Nika, Grigor
0a783ab4-5bb6-49f3-ae16-689ac42362d8
Gehlbach, Stephen H.
c8f87d84-badf-483d-85eb-d86647b98a51
Diez-Perez, Adolfo
19f89c53-003a-469c-92ac-69b0b979f3ec
Hooven, Frederick H.
75487234-9de4-4d47-a837-b72662e751ea
Adachi, Jonathan D.
b332030f-9df9-4fb8-8547-7192a37b2522
Adami, Silvano
cc35505b-b752-4ce0-a246-17e1de60a174
Anderson, Frederick A.
46c5965f-b6d7-4682-8435-ec8b085d2ed9
Boonen, Steven
fbfd999d-e425-406c-b66e-ca1b8150497b
Chapurlat, Roland
d9410f8c-4e4a-465b-8fb6-67efaadaad4c
Compston, Juliet E.
1038f0cb-dd36-49e5-8609-9091266faf67
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Delmas, Pierre
818c03cd-1ef6-4bf8-a5d2-9b4aa5019d98
Greenspan, Susan L.
bca80638-bd85-4682-8012-037c880dfd06
Lacroix, Andrea Z.
cd86dbf8-3782-4f89-a9d1-0d44f2a39b0a
Lindsay, Robert
9508787f-a0b6-4155-95f7-33c57e4f56a0
Netelenbos, J. Coen
9dbd9f31-46f9-4386-a2c9-8826897e652c
Pfeilschifter, Johannes
668ca581-77d4-4cfd-8621-ce542183b90e
Roux, Christian
1f852839-8036-423f-ade1-a003d42271fa
Saag, Kenneth G.
c9b4325d-9687-48a3-9985-0c7587650f31
Sambrook, Philip
2f7848ec-18b4-4bdd-9a9b-a9a767bf31b7
Silverman, Stuart
b3ed983a-c9f6-4029-babe-d5d9dce72375
Siris, Ethel S.
cc6622ff-fdce-4834-8edf-b9229094f755
Watts, Nelson B.
5c0d14e9-020d-4e1f-802a-163636c5f0ea
Nika, Grigor
0a783ab4-5bb6-49f3-ae16-689ac42362d8
Gehlbach, Stephen H.
c8f87d84-badf-483d-85eb-d86647b98a51

Diez-Perez, Adolfo, Hooven, Frederick H., Adachi, Jonathan D., Adami, Silvano, Anderson, Frederick A., Boonen, Steven, Chapurlat, Roland, Compston, Juliet E., Cooper, Cyrus, Delmas, Pierre, Greenspan, Susan L., Lacroix, Andrea Z., Lindsay, Robert, Netelenbos, J. Coen, Pfeilschifter, Johannes, Roux, Christian, Saag, Kenneth G., Sambrook, Philip, Silverman, Stuart, Siris, Ethel S., Watts, Nelson B., Nika, Grigor and Gehlbach, Stephen H. (2011) Regional differences in treatment for osteoporosis: The global longitudinal study of osteoporosis in women(GLOW). Bone, 49 (3), 493-498. (doi:10.1016/j.bone.2011.05.007). (PMID:21605715)

Record type: Article

Abstract

Among 58,009 women, current anti-osteoporosis medication use was lowest in Northern Europe (16%) and highest in USA and Australia (32%). Between 48% (USA, Southern Europe) and 68% (Northern Europe) of women aged ? 65 years with a history of spine or hip fracture since age 45 were untreated. Among women with osteoporosis, the percentage of treated cases was lowest in Europe (45–52% versus 62–65% elsewhere). Women with osteopenia and no other risk factors were treated with anti-osteoporosis medication most frequently in USA (31%) and Canada (31%), and least frequently in Southern Europe (12%), Northern Europe (13%), and Australia (16%). After adjusting for risk factors, US women were threefold as likely to be treated with anti-osteoporosis medication as Northern European women (odds ratio 2.8; 95% confidence interval 2.5–3.1) and 1.5 times as likely to be treated as Southern European women (1.5, 1.4–1.6). Up to half of women reporting previous hip or spine fracture did not receive treatment.

This record has no associated files available for download.

More information

Published date: 14 May 2011
Keywords: fracture, regional variation, women, risk factor, preventive treatment

Identifiers

Local EPrints ID: 194379
URI: http://eprints.soton.ac.uk/id/eprint/194379
ISSN: 8756-3282
PURE UUID: 831f684a-b2af-479e-b183-ab528c0ac5e8
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709

Catalogue record

Date deposited: 27 Jul 2011 13:52
Last modified: 18 Mar 2024 02:45

Export record

Altmetrics

Contributors

Author: Adolfo Diez-Perez
Author: Frederick H. Hooven
Author: Jonathan D. Adachi
Author: Silvano Adami
Author: Frederick A. Anderson
Author: Steven Boonen
Author: Roland Chapurlat
Author: Juliet E. Compston
Author: Cyrus Cooper ORCID iD
Author: Pierre Delmas
Author: Susan L. Greenspan
Author: Andrea Z. Lacroix
Author: Robert Lindsay
Author: J. Coen Netelenbos
Author: Johannes Pfeilschifter
Author: Christian Roux
Author: Kenneth G. Saag
Author: Philip Sambrook
Author: Stuart Silverman
Author: Ethel S. Siris
Author: Nelson B. Watts
Author: Grigor Nika
Author: Stephen H. Gehlbach

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×