Pathways activated during human asthma exacerbation as revealed by gene expression patterns in blood

Bjornsdottir, Unnur S., Holgate, Stephen T., Reddy, Padmalatha S., Hill, Andrew A., McKee, Charlotte M., Csimma, Cristina I., Weaver, Amy A., Legault, Holly M., Small, Clayton G., Ramsey, Renee C., Ellis, Debra K., Burke, Conor M., Thompson, Philip J., Howarth, Peter H., Wardlaw, Andrew J., Bardin, Phillip G., Bernstein, David I., Irving, Louis B., Chupp, Geoffrey L., Bensch, George W., Bensch, Gregory W., Stahlman, Jon E., Karetzky, Monroe, Baker, James, Miller, Rachel L., Goodman, Brad H., Raible, Donald G., Goldman, Samuel J., Miller, Douglas K., Ryan, John L., Dorner, Andrew J., Immermann, Frederick W. and O'Toole, Margot (2011) Pathways activated during human asthma exacerbation as revealed by gene expression patterns in blood. PloS One, 6, (7), e21902-[19pp]. (doi:10.1371/journal.pone.0021902) (PMID:3136489)

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Description/Abstract

This study has shown that analysis of PBMCs reveals systemic changes accompanying asthma exacerbation and has laid the foundation for future comparative studies using PBMCs.

Item Type:Article
ISSN:1932-6203 (electronic)
Subjects:Q Science > QH Natural history > QH426 Genetics
Q Science > QR Microbiology > QR180 Immunology
R Medicine > RB Pathology
Divisions:Faculty of Medicine > Infection, Inflammation and Immunity
ePrint ID:194677
URI:http://eprints.soton.ac.uk/id/eprint/194677
Deposited On:09 Aug 2011 14:41
Last Modified:01 Sep 2011 17:15

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