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Palladium-catalysed nucleophilic release of allylic amines from a phenolic resin

Fisher, M. and Brown, R. C. D. (2001) Palladium-catalysed nucleophilic release of allylic amines from a phenolic resin. Tetrahedron Letters, 42, (46), 8227-8230. (doi:10.1016/S0040-4039(01)01739-7)

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Official URL: http://dx.doi.org/10.1016/S0040-4039(01)01739-7

Description/Abstract

2 circle Allylic alcohols were coupled to phenolic polystyrene resin under Mitsunobu conditions to provide substituted allyl ethers. which underwent efficient nucleophilic cleavage by 1 degrees and 2 degrees amines in the presence of catalytic palladium to afford allylic amines.

Item Type:Article
Uncontrolled Keywords:solid-phase synthesis, organic-synthesis, combinatorial chemistry, linkers
Related URLs:http://dx.doi.org/10.1016/S004...01)01739-7
Subjects:Q Science
Q Science > QD Chemistry
Divisions:University Structure - Pre August 2011 > School of Chemistry
ePrint ID:19477
Deposited On:14 Feb 2006
Last Modified:01 Jun 2011 09:33

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