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Exposure, uptake, distribution and toxicity of nanomaterials in humans

Exposure, uptake, distribution and toxicity of nanomaterials in humans
Exposure, uptake, distribution and toxicity of nanomaterials in humans
The last decade has witnessed an unprecedented explosion in nanotechnology to take advantage of the unique physicochemical properties that emerge at the nanoscale including quantum effects. However, the excitement generated by new applications of nanotechnology in products has not been matched by a parallel appreciation or understanding of their potential toxic effects in humans and the wider ecology. This review draws some parallels to what we already know about the toxicity of particles in the workplace and in association with air pollution, and then discusses what is known about the toxicology of nanomaterials in mammals including humans. The review identifies substantial gaps in knowledge and makes some recommendations for future research.
1550-7033
1-19
Holgate, Stephen T.
2e7c17a9-6796-436e-8772-1fe6d2ac5edc
Holgate, Stephen T.
2e7c17a9-6796-436e-8772-1fe6d2ac5edc

Holgate, Stephen T. (2010) Exposure, uptake, distribution and toxicity of nanomaterials in humans. Journal of Biomedical Nanotechnology, 6 (1), 1-19. (doi:10.1166/jbn.2010.1098). (PMID:20499827)

Record type: Article

Abstract

The last decade has witnessed an unprecedented explosion in nanotechnology to take advantage of the unique physicochemical properties that emerge at the nanoscale including quantum effects. However, the excitement generated by new applications of nanotechnology in products has not been matched by a parallel appreciation or understanding of their potential toxic effects in humans and the wider ecology. This review draws some parallels to what we already know about the toxicity of particles in the workplace and in association with air pollution, and then discusses what is known about the toxicology of nanomaterials in mammals including humans. The review identifies substantial gaps in knowledge and makes some recommendations for future research.

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More information

Published date: February 2010
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 195239
URI: http://eprints.soton.ac.uk/id/eprint/195239
ISSN: 1550-7033
PURE UUID: 97e66071-be96-4a86-906e-626a4bdd1804

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Date deposited: 17 Aug 2011 14:24
Last modified: 14 Mar 2024 04:03

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