Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation


Ranasinghe, R.T., Brown, L.J. and Brown, T. (2001) Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation. Chemical Communications, (16), 1480-1481. (doi:10.1039/b104421b).

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Description/Abstract

Linear, single stranded probes incorporating a fluorophore and an acridine moiety are weakly fluorescent until hybridised to a complementary target nucleic acid whereupon fluorescence increases due to reduced quenching.

Item Type: Article
ISSNs: 1359-7345 (print)
1364-548X (electronic)
Keywords: molecular beacons, mutation
Subjects: Q Science > QD Chemistry
Divisions: University Structure - Pre August 2011 > School of Chemistry
ePrint ID: 19605
Date Deposited: 14 Feb 2006
Last Modified: 27 Mar 2014 18:09
URI: http://eprints.soton.ac.uk/id/eprint/19605

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