Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation
Ranasinghe, R.T., Brown, L.J. and Brown, T. (2001) Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation. Chemical Communications, (16), 1480-1481. (doi:10.1039/b104421b).
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Description/Abstract
Linear, single stranded probes incorporating a fluorophore and an acridine moiety are weakly fluorescent until hybridised to a complementary target nucleic acid whereupon fluorescence increases due to reduced quenching.
| Item Type: | Article |
|---|---|
| ISSNs: | 1359-7345 (print) 1364-548X (electronic) |
| Keywords: | molecular beacons, mutation |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | University Structure - Pre August 2011 > School of Chemistry |
| Item ID: | 19605 |
| Date Deposited: | 14 Feb 2006 |
| Last Modified: | 25 Apr 2013 10:41 |
| Contributors: | Ranasinghe, R.T. (Author) Brown, L.J. (Author) Brown, T. (Author) |
| Date: | 21 August 2001 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/19605 |
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