Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation
Ranasinghe, R. T., Brown, L. J. and Brown, T. (2001) Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation. Chemical Communications, (16), 1480-1481. (doi: 10.1039/b104421b)
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Description/Abstract
Linear, single stranded probes incorporating a fluorophore and an acridine moiety are weakly fluorescent until hybridised to a complementary target nucleic acid whereupon fluorescence increases due to reduced quenching.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | molecular beacons, mutation |
| Related URLs: | http://www.rsc.org/Publishing/...i=b104421b |
| Subjects: | Q Science Q Science > QD Chemistry |
| Divisions: | University Structure - Pre August 2011 > School of Chemistry |
| ePrint ID: | 19605 |
| URI: | http://eprints.soton.ac.uk/id/eprint/19605 |
| Deposited On: | 14 Feb 2006 |
| Last Modified: | 01 Jun 2011 12:03 |
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