Lung resection for the treatment of severe localised bronchiectasis in cystic fibrosis patients


Dalrymple-Hay, M. J, Lucas, J.S., Connett, G. and Lea, R. E. (1999) Lung resection for the treatment of severe localised bronchiectasis in cystic fibrosis patients. Acta Chirurgica Hungarica, 38, (1), 23-25. (PMID:10439089).

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Description/Abstract

BACKGROUND: A small proportion of cystic fibrosis patients develop severe localised bronchiectasis. When this persists despite maximal medical therapy it presents a difficult management problem. Lung transplantation cannot be justified. We report encouraging results in six patients with severe localised bronchiectasis and cystic fibrosis who underwent pulmonary resection.

METHODS: Each child had severe localised bronchiectasis despite maximal medical therapy. Intensive preoperative toilet was instituted and pulmonary resection undertaken when lung function was optimal.

RESULTS: There was a marked improvement in symptoms in every case. No significant long-standing morbidity was associated with the resection. There was no significant decrease in pulmonary function following resection.

CONCLUSION: Pulmonary resection should be considered in the management of severe localised bronchiectasis unresponsive to maximal medical therapy in cystic fibrosis patients.

Item Type: Article
ISSNs: 0231-4614 (print)
Subjects: R Medicine > RD Surgery
R Medicine > RJ Pediatrics
R Medicine > RM Therapeutics. Pharmacology
Divisions: Faculty of Medicine > Infection, Inflammation and Immunity
ePrint ID: 198837
Date Deposited: 07 Oct 2011 15:54
Last Modified: 27 Mar 2014 19:46
URI: http://eprints.soton.ac.uk/id/eprint/198837

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