Lung resection for the treatment of severe localised bronchiectasis in cystic fibrosis patients
Lung resection for the treatment of severe localised bronchiectasis in cystic fibrosis patients
BACKGROUND: A small proportion of cystic fibrosis patients develop severe localised bronchiectasis. When this persists despite maximal medical therapy it presents a difficult management problem. Lung transplantation cannot be justified. We report encouraging results in six patients with severe localised bronchiectasis and cystic fibrosis who underwent pulmonary resection.
METHODS: Each child had severe localised bronchiectasis despite maximal medical therapy. Intensive preoperative toilet was instituted and pulmonary resection undertaken when lung function was optimal.
RESULTS: There was a marked improvement in symptoms in every case. No significant long-standing morbidity was associated with the resection. There was no significant decrease in pulmonary function following resection.
CONCLUSION: Pulmonary resection should be considered in the management of severe localised bronchiectasis unresponsive to maximal medical therapy in cystic fibrosis patients.
23-25
Dalrymple-Hay, M. J
0084f7bc-84d8-4079-bf1f-bc37446f076f
Lucas, J.S.
5cb3546c-87b2-4e59-af48-402076e25313
Connett, G.
55d5676c-90d8-46bf-a508-62eded276516
Lea, R. E.
006d048f-38ab-4faf-9e8f-c64ecc1d07ab
1999
Dalrymple-Hay, M. J
0084f7bc-84d8-4079-bf1f-bc37446f076f
Lucas, J.S.
5cb3546c-87b2-4e59-af48-402076e25313
Connett, G.
55d5676c-90d8-46bf-a508-62eded276516
Lea, R. E.
006d048f-38ab-4faf-9e8f-c64ecc1d07ab
Dalrymple-Hay, M. J, Lucas, J.S., Connett, G. and Lea, R. E.
(1999)
Lung resection for the treatment of severe localised bronchiectasis in cystic fibrosis patients.
Acta Chirurgica Hungarica, 38 (1), .
(PMID:10439089)
Abstract
BACKGROUND: A small proportion of cystic fibrosis patients develop severe localised bronchiectasis. When this persists despite maximal medical therapy it presents a difficult management problem. Lung transplantation cannot be justified. We report encouraging results in six patients with severe localised bronchiectasis and cystic fibrosis who underwent pulmonary resection.
METHODS: Each child had severe localised bronchiectasis despite maximal medical therapy. Intensive preoperative toilet was instituted and pulmonary resection undertaken when lung function was optimal.
RESULTS: There was a marked improvement in symptoms in every case. No significant long-standing morbidity was associated with the resection. There was no significant decrease in pulmonary function following resection.
CONCLUSION: Pulmonary resection should be considered in the management of severe localised bronchiectasis unresponsive to maximal medical therapy in cystic fibrosis patients.
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Published date: 1999
Organisations:
Clinical & Experimental Sciences
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Local EPrints ID: 198837
URI: http://eprints.soton.ac.uk/id/eprint/198837
ISSN: 0231-4614
PURE UUID: d677f937-8f0f-4b9a-b4d2-28e4f805fe4c
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Date deposited: 07 Oct 2011 15:54
Last modified: 20 Feb 2024 03:03
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Author:
M. J Dalrymple-Hay
Author:
G. Connett
Author:
R. E. Lea
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