Aging, sarcopenia and the life-course

Sayer, Avan Aihie and Cooper, Cyrus (2006) Aging, sarcopenia and the life-course. Reviews in Clinical Gerontology, 16, (4), 265-274. (doi:10.1017/S0959259807002225).


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There is growing support for characterizing human aging from a life-course perspective, in terms of recognizing important influences operating from conception to death, and this approach provides a framework for understanding aging processes operating at the individual level. Kirkwood's disposable soma theory proposes that aging is a manifestation of imperfect somatic maintenance and repair processes. We can therefore predict that differing exposure to the determinants of somatic damage across the life-course, and variable capacity to respond in terms of repair are likely to underlie the wide variation in rates of aging between individuals

Item Type: Article
ISSNs: 0959-2598 (print)
1469-9036 (electronic)
Related URLs:
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine
Divisions: Faculty of Medicine
ePrint ID: 199457
Date Deposited: 14 Oct 2011 13:34
Last Modified: 27 Mar 2014 19:46

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