Synthesis of HyBeacons and dual-labelled probes containing 2'- fluorescent groups for use in genetic analysis
Dobson, N., McDowell, D.G., French, D.J., Brown, L.J., Mellor, J.M. and Brown, T. (2003) Synthesis of HyBeacons and dual-labelled probes containing 2'- fluorescent groups for use in genetic analysis. Chemical Communications, (11), 1234-1235. (doi:10.1039/b302855k).
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Description/Abstract
An FMOC-protected 2A-hydroxyethyl uridine phosphoramidite has been used to synthesise fluorescein-labelled HyBeacon probes and "FAM-ROX" dual-labelled fluorogenic oligonucleotides.
| Item Type: | Article |
|---|---|
| ISSNs: | 1359-7345 (print) 1364-548X (electronic) |
| Keywords: | fluorescence, oligonucleotides, derivatives, 2', -position |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | University Structure - Pre August 2011 > School of Chemistry |
| Item ID: | 19946 |
| Date Deposited: | 21 Feb 2006 |
| Last Modified: | 25 Apr 2013 10:46 |
| Contributors: | Dobson, N. (Author) McDowell, D.G. (Author) French, D.J. (Author) Brown, L.J. (Author) Mellor, J.M. (Author) Brown, T. (Author) |
| Date: | 2003 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/19946 |
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