Synthesis of HyBeacons and dual-labelled probes containing 2'- fluorescent groups for use in genetic analysis


Dobson, N., McDowell, D.G., French, D.J., Brown, L.J., Mellor, J.M. and Brown, T. (2003) Synthesis of HyBeacons and dual-labelled probes containing 2'- fluorescent groups for use in genetic analysis. Chemical Communications, (11), 1234-1235. (doi:10.1039/b302855k).

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Description/Abstract

An FMOC-protected 2A-hydroxyethyl uridine phosphoramidite has been used to synthesise fluorescein-labelled HyBeacon probes and "FAM-ROX" dual-labelled fluorogenic oligonucleotides.

Item Type: Article
ISSNs: 1359-7345 (print)
1364-548X (electronic)
Keywords: fluorescence, oligonucleotides, derivatives, 2&#39, -position
Subjects: Q Science > QD Chemistry
Divisions: University Structure - Pre August 2011 > School of Chemistry
ePrint ID: 19946
Date Deposited: 21 Feb 2006
Last Modified: 27 Mar 2014 18:09
URI: http://eprints.soton.ac.uk/id/eprint/19946

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