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Synthesis of HyBeacons and dual-labelled probes containing 2'- fluorescent groups for use in genetic analysis

Synthesis of HyBeacons and dual-labelled probes containing 2'- fluorescent groups for use in genetic analysis
Synthesis of HyBeacons and dual-labelled probes containing 2'- fluorescent groups for use in genetic analysis
An FMOC-protected 2A-hydroxyethyl uridine phosphoramidite has been used to synthesise fluorescein-labelled HyBeacon probes and "FAM-ROX" dual-labelled fluorogenic oligonucleotides.
fluorescence, oligonucleotides, derivatives, 2&#39, -position
1359-7345
1234-1235
Dobson, N.
e80b9d0f-4871-4c11-a0d8-aaa71c8e0319
McDowell, D.G.
30e07793-9137-40ea-90ca-7752ddd2e7e7
French, D.J.
e7221974-9b57-44a5-9cfb-1260526131fa
Brown, L.J.
75aa95fa-5d27-46a7-9dbe-0f465a664f5b
Mellor, J.M.
116e0a09-9f67-4a1e-8110-9a6f27772ed3
Brown, T.
a64aae36-bb30-42df-88a2-11be394e8c89
Dobson, N.
e80b9d0f-4871-4c11-a0d8-aaa71c8e0319
McDowell, D.G.
30e07793-9137-40ea-90ca-7752ddd2e7e7
French, D.J.
e7221974-9b57-44a5-9cfb-1260526131fa
Brown, L.J.
75aa95fa-5d27-46a7-9dbe-0f465a664f5b
Mellor, J.M.
116e0a09-9f67-4a1e-8110-9a6f27772ed3
Brown, T.
a64aae36-bb30-42df-88a2-11be394e8c89

Dobson, N., McDowell, D.G., French, D.J., Brown, L.J., Mellor, J.M. and Brown, T. (2003) Synthesis of HyBeacons and dual-labelled probes containing 2'- fluorescent groups for use in genetic analysis. Chemical Communications, (11), 1234-1235. (doi:10.1039/b302855k).

Record type: Article

Abstract

An FMOC-protected 2A-hydroxyethyl uridine phosphoramidite has been used to synthesise fluorescein-labelled HyBeacon probes and "FAM-ROX" dual-labelled fluorogenic oligonucleotides.

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More information

Published date: 2003
Keywords: fluorescence, oligonucleotides, derivatives, 2&#39, -position
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Identifiers

Local EPrints ID: 19946
URI: http://eprints.soton.ac.uk/id/eprint/19946
DOI: doi:10.1039/b302855k
ISSN: 1359-7345
PURE UUID: ef4ea74e-9203-4dda-8fa1-dce83c680189
ORCID for L.J. Brown: ORCID iD orcid.org/0000-0002-5678-0814

Catalogue record

Date deposited: 21 Feb 2006
Last modified: 16 Mar 2024 03:00

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Contributors

Author: N. Dobson
Author: D.G. McDowell
Author: D.J. French
Author: L.J. Brown ORCID iD
Author: J.M. Mellor
Author: T. Brown

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