Vitamin D and the postmenopausal population
Holroyd, Christopher, Cooper, Cyrus and Harvey, Nicholas C. (2011) Vitamin D and the postmenopausal population. Menopause International, 17, (3), 102-107. (doi:10.1258/mi.2011.011025 ). (PMID:21903714).
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Description/Abstract
Vitamin D, a hormone critical to the body's maintenance of serum calcium and phosphorus concentrations, is currently the subject of much scientific interest. Low levels of vitamin D have been observed in many populations and epidemiological studies have suggested a link between this biochemical state and a range of diseases, such as cancer, diabetes and multiple sclerosis. While the consequence of vitamin D deficiency is well documented for bone (rickets and osteomalacia), with mixed findings relating to falls and fractures, a causal link between vitamin D deficiency and these wider health outcomes has not been established. If these relationships were found to be causal, the morbidity and mortality resulting from low levels of vitamin D could be substantial; the current evidence base, however, most robustly supports the assessment of serum 25(OH)-vitamin D in the context of specific symptoms, low bone mineral density or biochemical abnormalities, rather than as an entity to treat in its own right or as the basis for a population-wide screening programme.
| Item Type: | Article |
|---|---|
| ISSNs: | 1754-0453 (print) 1754-0461 (electronic) |
| Related URLs: | |
| Keywords: | vitamin D, calcium, deficiency, insufficiency, PTH, falls, fractures |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine |
| Item ID: | 199675 |
| Date Deposited: | 18 Oct 2011 11:36 |
| Last Modified: | 02 Mar 2012 14:00 |
| Contributors: | Holroyd, Christopher (Author) Cooper, Cyrus (Author) Harvey, Nicholas C. (Author) |
| Date: | September 2011 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/199675 |
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