A test for the number of coupled spins I = 1/2 in magic-angle-spinning solids: zero-quantum recoupling of multiple-quantum coherences
A test for the number of coupled spins I = 1/2 in magic-angle-spinning solids: zero-quantum recoupling of multiple-quantum coherences
Current methodologies for estimating the number of coupled spins I=1/2 in solids are based upon the maximum multiple-quantum order that can be observed. This strategy establishes a clear lower bound on the number of coupled spins I=1/2. However, it is difficult to ascertain the exact number of coupled spins, since the absence of a peak could be due either to the limited size of the spin system or to the experimental difficulty of exciting high-quantum orders and recovering those coherences into detectable signals. Herein, a supplementary test is proposed that allows one to determine whether a given coherence has the highest possible order in the spin system. The sample is subjected to magic-angle spinning and the behaviour of the coherence under a rotor-synchronised spin-echo sequence is compared to its behaviour under a zero-quantum recoupling sequence. A similar decay of the coherence in these two experiments is strong evidence for the coherence order being the maximum possible. We propose applications to biomolecular solid-state NMR spectroscopy.
magic-angle spinning, multiple-quantum coherence, nmr spectroscopy, peptides, solid-state spectroscopy, spin counting, nuclear-magnetic-resonance, echo double-resonance, state nmr, rotatingsolids, pulse sequences, spectroscopy, excitation, dynamics, simulation, peptide
457-465
Hughes, Colan E.
5054ad30-ed83-4835-9dde-0fafad016711
Schmedt auf der Günne, Jörn
cf66631b-52b3-4280-a696-17853a6e7322
Levitt, Malcolm H.
bcc5a80a-e5c5-4e0e-9a9a-249d036747c3
16 May 2003
Hughes, Colan E.
5054ad30-ed83-4835-9dde-0fafad016711
Schmedt auf der Günne, Jörn
cf66631b-52b3-4280-a696-17853a6e7322
Levitt, Malcolm H.
bcc5a80a-e5c5-4e0e-9a9a-249d036747c3
Hughes, Colan E., Schmedt auf der Günne, Jörn and Levitt, Malcolm H.
(2003)
A test for the number of coupled spins I = 1/2 in magic-angle-spinning solids: zero-quantum recoupling of multiple-quantum coherences.
ChemPhysChem, 4 (5), .
(doi:10.1002/cphc.200200470).
Abstract
Current methodologies for estimating the number of coupled spins I=1/2 in solids are based upon the maximum multiple-quantum order that can be observed. This strategy establishes a clear lower bound on the number of coupled spins I=1/2. However, it is difficult to ascertain the exact number of coupled spins, since the absence of a peak could be due either to the limited size of the spin system or to the experimental difficulty of exciting high-quantum orders and recovering those coherences into detectable signals. Herein, a supplementary test is proposed that allows one to determine whether a given coherence has the highest possible order in the spin system. The sample is subjected to magic-angle spinning and the behaviour of the coherence under a rotor-synchronised spin-echo sequence is compared to its behaviour under a zero-quantum recoupling sequence. A similar decay of the coherence in these two experiments is strong evidence for the coherence order being the maximum possible. We propose applications to biomolecular solid-state NMR spectroscopy.
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Published date: 16 May 2003
Keywords:
magic-angle spinning, multiple-quantum coherence, nmr spectroscopy, peptides, solid-state spectroscopy, spin counting, nuclear-magnetic-resonance, echo double-resonance, state nmr, rotatingsolids, pulse sequences, spectroscopy, excitation, dynamics, simulation, peptide
Identifiers
Local EPrints ID: 19984
URI: http://eprints.soton.ac.uk/id/eprint/19984
ISSN: 1439-4235
PURE UUID: be42e97d-cd9c-4489-99db-fdb9e87b82d2
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Date deposited: 24 Feb 2006
Last modified: 16 Mar 2024 03:18
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Author:
Colan E. Hughes
Author:
Jörn Schmedt auf der Günne
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