Solid-phase construction: high efficiency dendrimer synthesis using AB(3) isocyanate-type monomers
Lebreton, S., How, S. E., Buchholz, M., Yingyongnarongkul, B. E. and Bradley, M. (2003) Solid-phase construction: high efficiency dendrimer synthesis using AB(3) isocyanate-type monomers. Tetrahedron, 59, (22), 3945-3953. (doi:10.1016/S0040-4020(03)00463-0).
Download
Full text not available from this repository.
Description/Abstract
Solid-phase synthesis is an ideal tool for reactions that require high concentrations and excess reagents and forcing chemical conditions. One such chemistry is that required for dendrimer construction. In this paper the synthesis of a series of symmetrical AB(3) isocyanate-type monomers is reported and used for the preparation of tri-branched dendrimers on the solid-phase. This method not only allows isolable dendrimer but can generate high-loading supports and devices for multivalent presentation.
| Item Type: | Article |
|---|---|
| Related URLs: | |
| Keywords: | solid-phase chemistry, dendrimers, high-loading, multivalency, isocyanatehigh-loading resin, peptide-synthesis, beads, chemistry |
| Subjects: | Q Science Q Science > QD Chemistry |
| Divisions: | University Structure - Pre August 2011 > School of Chemistry |
| Item ID: | 20008 |
| Date Deposited: | 17 Feb 2006 |
| Last Modified: | 01 Jun 2011 03:56 |
| Contributors: | Lebreton, S. (Author) How, S. E. (Author) Buchholz, M. (Author) Yingyongnarongkul, B. E. (Author) Bradley, M. (Author) |
| Date: | 26 May 2003 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/20008 |
Actions (login required)
 |
View Item |
