The first synthesis of glucosylgalactosyl hydroxylysine (Glu-Gal-Hyl) an important biological indicator of collagen turnover
Allevi, Pietro, Anastasia, Mario, Paroni, Rita and Ragusa, Andrea (2004) The first synthesis of glucosylgalactosyl hydroxylysine (Glu-Gal-Hyl) an important biological indicator of collagen turnover. Bioorganic & Medicinal Chemistry Letters, 14, (12), 3319-3321. (doi: 10.1016/j.bmcl.2004.03.068)
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Official URL: http://dx.doi.org/10.1016/j.bmcl.2004.03.068
Description/Abstract
This paper reports the first chemical synthesis of α-D-glucopyranosyl-(1 --> 2)-β-D-galactopyranosyl-O-hydroxylysine, a glycoside of hydroxylysine important as indicator of skin and bone collagen turnover, starting with commercial compounds.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | glucosylgalactosyl hydroxylysine, collagen turnover markers, glycosylated (l)-delta-hydroxylysine.glomerular basement-membrane, solid-phase synthesis, biochemicalinterest, urinary-excretion, modular synthesis, building-block, glycosides, pyridinoline, glycopeptide, deoxypyridinoline |
| Related URLs: | http://www.ncbi.nlm.nih.gov/en...med_docsum http://dx.doi.org/10.1016/j.bm...004.03.068 |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | University Structure - Pre August 2011 > School of Chemistry |
| ePrint ID: | 20117 |
| URI: | http://eprints.soton.ac.uk/id/eprint/20117 |
| Deposited On: | 23 Feb 2006 |
| Last Modified: | 01 Jun 2011 09:35 |
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