The demonstration of an enhanced microelectrochemical transistor for measurements in neutral solution at low analyte concentration

Astier, Y. and Bartlett, P.N. (2004) The demonstration of an enhanced microelectrochemical transistor for measurements in neutral solution at low analyte concentration. Bioelectrochemistry, 64, (1), 15-22. (doi: 10.1016/j.bioelechem.2003.12.008).

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Original Publication URL: http://dx.doi.org/10.1016/j.bioelechem.2003.12.008

Description/Abstract

We report a new, sensitive detection method for the measurement of analytes based on the combination of conducting polymer technology and redox enzyme electrochemistry. This method provides a simple measurement method potentially enabling point of care testing on disposable electrodes in under 60 s. The measurement does not require a reference or counter electrode and the analytical signal is recorded by an ammeter measuring milliampere currents through a polymer transistor. Even at very low analyte concentration, the signal is not subject to significant noise.

Item Type:	Article
Related URLs:	http://www.ncbi.nlm.nih.gov/en...med_docsum http://dx.doi.org/10.1016/j.bi...003.12.008
Keywords:	microelectrochemical transistor, neutral solution, analyte alkaline-phosphatase, enzyme switch, chemical derivatization, aminophenyl phosphate, electronic devices, composite films,conductivity, fabrication, polyaniline, poly(3-methylthiophene
Subjects:	T Technology > TP Chemical technology Q Science > QD Chemistry
Divisions:	University Structure - Pre August 2011 > School of Chemistry
Item ID:	20121
Date Deposited:	23 Feb 2006
Last Modified:	31 May 2011 23:32
Contributors:	Astier, Y. (Author) Bartlett, P.N. (Author)
Date:	1 August 2004
Status:	Published
URI:	http://eprints.soton.ac.uk/id/eprint/20121

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