An analogue of adenine that forms an 'A : T' base pair of comparable stability to G : C
Booth, J., Cummins, W. J. and Brown, T. (2004) An analogue of adenine that forms an 'A : T' base pair of comparable stability to G : C. Chemical Communications, (19), 2208-2209. (doi: 10.1039/b409155h).
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Original Publication URL: http://www.rsc.org/Publishing/Journals/CC/article....
Description/Abstract
The heterocyclic base 7-aminopropargyl-7-deaza-2,6-diaminopurine (D) has been incorporated into oligodeoxynucleotides. D: T has similar thermodynamic stability to G:C and is a stable analogue of A:T.
| Item Type: | Article |
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| Related URLs: | |
| Keywords: | dna, oligonucleotides, duplex, pyrimidines |
| Subjects: | Q Science Q Science > QD Chemistry |
| Divisions: | University Structure - Pre August 2011 > School of Chemistry |
| Item ID: | 20142 |
| Date Deposited: | 22 Feb 2006 |
| Last Modified: | 25 Apr 2013 10:50 |
| Contributors: | Booth, J. (Author) Cummins, W. J. (Author) Brown, T. (Author) |
| Date: | 2004 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/20142 |
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