Effects of temperature and humidity on the efficacy of methicillin-resistant Staphylococcus aureus challenged antimicrobial materials containing silver and copper


Michels, H.T., Noyce, J.O. and Keevil, C.W. (2009) Effects of temperature and humidity on the efficacy of methicillin-resistant Staphylococcus aureus challenged antimicrobial materials containing silver and copper. Letters in Applied Microbiology, 49, (2), 191-195. (doi:10.1111/j.1472-765X.2009.02637.x). (PMID:19413757).

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Description/Abstract

Aims: to compare silver and copper, metals with known antimicrobial properties, by evaluating the effects of temperature and humidity on efficacy by challenging with methicillin resistant Staphylococcus aureus (MRSA).

Methods and results: using standard methodology described in a globally used Japanese Industrial Standard, JIS Z 2801, a silver ion-containing material exhibited >5 log reduction in MRSA viability after 24 h at >90% relative humidity (RH) at 20°C and 35°C but only a <0·3 log at ∼22% RH and 20°C and no reduction at ∼22% RH and 35°C. Copper alloys demonstrated >5 log reductions under all test conditions.

Conclusions: while the high humidity (>90% RH) and high temperature (35°C) utilized in JIS Z 2801 produce measurable efficacy in a silver ion-containing material, it showed no significant response at lower temperature and humidity levels typical of indoor environments.

Significance and Impact of the Study:  The high efficacy levels displayed by the copper alloys, at temperature and humidity levels typical of indoor environments, compared to the low efficacy of the silver ion-containing material under the same conditions, favours the use of copper alloys as antimicrobial materials in indoor environments such as hospitals

Item Type: Article
ISSNs: 0266-8254 (print)
1472-765X (electronic)
Subjects: Q Science > QR Microbiology
Divisions: Faculty of Natural and Environmental Sciences > Biological Sciences
ePrint ID: 209313
Date Deposited: 27 Jan 2012 15:22
Last Modified: 27 Mar 2014 19:50
URI: http://eprints.soton.ac.uk/id/eprint/209313

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