Effects of temperature and humidity on the efficacy of methicillin-resistant Staphylococcus aureus challenged antimicrobial materials containing silver and copper
Michels, H.T., Noyce, J.O. and Keevil, C.W. (2009) Effects of temperature and humidity on the efficacy of methicillin-resistant Staphylococcus aureus challenged antimicrobial materials containing silver and copper. Letters in Applied Microbiology, 49, (2), 191-195. (doi:10.1111/j.1472-765X.2009.02637.x). (PMID:19413757).
Download
Full text not available from this repository.
Description/Abstract
Aims: to compare silver and copper, metals with known antimicrobial properties, by evaluating the effects of temperature and humidity on efficacy by challenging with methicillin resistant Staphylococcus aureus (MRSA).
Methods and results: using standard methodology described in a globally used Japanese Industrial Standard, JIS Z 2801, a silver ion-containing material exhibited >5 log reduction in MRSA viability after 24 h at >90% relative humidity (RH) at 20°C and 35°C but only a <0·3 log at ∼22% RH and 20°C and no reduction at ∼22% RH and 35°C. Copper alloys demonstrated >5 log reductions under all test conditions.
Conclusions: while the high humidity (>90% RH) and high temperature (35°C) utilized in JIS Z 2801 produce measurable efficacy in a silver ion-containing material, it showed no significant response at lower temperature and humidity levels typical of indoor environments.
Significance and Impact of the Study: The high efficacy levels displayed by the copper alloys, at temperature and humidity levels typical of indoor environments, compared to the low efficacy of the silver ion-containing material under the same conditions, favours the use of copper alloys as antimicrobial materials in indoor environments such as hospitals
| Item Type: | Article |
|---|---|
| ISSNs: | 0266-8254 (print) 1472-765X (electronic) |
| Subjects: | Q Science > QR Microbiology |
| Divisions: | Faculty of Natural and Environmental Sciences > Biological Sciences |
| Item ID: | 209313 |
| Date Deposited: | 27 Jan 2012 15:22 |
| Last Modified: | 31 Jan 2012 13:36 |
| Contributors: | Michels, H.T. (Author) Noyce, J.O. (Author) Keevil, C.W. (Author) |
| Date: | August 2009 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/209313 |
Actions (login required)
 |
View Item |
