Tunable transmembrane chloride transport by bis-indolylureas


Haynes, Cally J.E., Moore, Stephen J., Hiscock, Jennifer R., Marques, Igor, Costa, Paulo Jorge, Félix, Vítor and Gale, Philip A. (2012) Tunable transmembrane chloride transport by bis-indolylureas. Chemical Science, 3, 1436-1444. (doi:10.1039/C2SC20041D).

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Description/Abstract

A series of bis-indolylureas have been found to mediate chloride transport across vesicle bilayers. The anion transport activity of these receptors may be readily modulated by small structural changes to the receptor scaffold as shown by the combination of experimental chloride efflux studies and molecular dynamics simulations in water and POPC bilayer

Item Type: Article
ISSNs: 2041-6520 (print)
2041-6539 (electronic)
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Natural and Environmental Sciences > Chemistry > Electrochemistry & Surface Science Group
Item ID: 210962
Date Deposited: 16 Feb 2012 15:26
Last Modified: 03 Apr 2012 07:46
Contributors: Haynes, Cally J.E. (Author)
Moore, Stephen J. (Author)
Hiscock, Jennifer R. (Author)
Marques, Igor (Author)
Costa, Paulo Jorge (Author)
Félix, Vítor (Author)
Gale, Philip A. (Author)
Date: 9 February 2012
Status: Unpublished
URI: http://eprints.soton.ac.uk/id/eprint/210962

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