Tunable transmembrane chloride transport by bis-indolylureas


Haynes, Cally J.E., Moore, Stephen J., Hiscock, Jennifer R., Marques, Igor, Costa, Paulo Jorge, Félix, Vítor and Gale, Philip A. (2012) Tunable transmembrane chloride transport by bis-indolylureas. Chemical Science, 3, 1436-1444. (doi:10.1039/C2SC20041D).

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Description/Abstract

A series of bis-indolylureas have been found to mediate chloride transport across vesicle bilayers. The anion transport activity of these receptors may be readily modulated by small structural changes to the receptor scaffold as shown by the combination of experimental chloride efflux studies and molecular dynamics simulations in water and POPC bilayer

Item Type: Article
ISSNs: 2041-6520 (print)
2041-6539 (electronic)
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Natural and Environmental Sciences > Chemistry > Electrochemistry & Surface Science Group
ePrint ID: 210962
Date Deposited: 16 Feb 2012 15:26
Last Modified: 14 Apr 2014 11:10
Projects:
Selective Receptors for the Transmembrane Transport of Bicarbonate Anion
Funded by: EPSRC (EP/G002576/1)
Led by: Philip Alan Gale
1 October 2008 to 31 March 2012
URI: http://eprints.soton.ac.uk/id/eprint/210962

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