The specific uptake size index for quantifying radiopharmaceutical uptake
Fleming, John S., Bolt, Livia, Stratford, Jennifer S. and Kemp, Paul M. (2004) The specific uptake size index for quantifying radiopharmaceutical uptake. Physics in medicine and biology, 49, (14), N227-N234. (doi:10.1088/0031-9155/49/14/N03)
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Official URL: http://dx.doi.org/10.1088/0031-9155/49/14/N03
Description/Abstract
Quantitative indices of radionuclide uptake in an object of interest provide a useful adjunct to qualitative interpretation in the diagnostic application of radionuclide imaging. This note describes a new measure of total uptake of an organ, the specific uptake size index (SUSI). It can either be related in absolute terms to the total activity injected or to the specific activity in a reference region. As it depends on the total activity in the object, the value obtained will not depend on the resolution of the imaging process, as is the case with some other similar quantitative indices. This has been demonstrated in an experiment using simulated images. The application of the index to quantification of dopamine receptor SPECT imaging and parathyroid–thyroid subtraction planar scintigraphy is described. The index is considered to be of potential value in reducing variation in quantitative assessment of uptake in objects with applications in all areas of radionuclide imaging.
| Item Type: | Article |
|---|---|
| ISSN: | 0031-9155 (print) |
| Related URLs: | http://www.ncbi.nlm.nih.gov/en...s=15357202 http://dx.doi.org/10.1088/0031.../49/14/N03 |
| Subjects: | R Medicine |
| Divisions: | University Structure - Pre August 2011 > School of Medicine > Developmental Origins of Health and Disease University Structure - Pre August 2011 > School of Medicine > Clinical Neurosciences |
| ePrint ID: | 25495 |
| URI: | http://eprints.soton.ac.uk/id/eprint/25495 |
| Deposited On: | 11 Apr 2006 |
| Last Modified: | 01 Jun 2011 00:41 |
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