Prenatal sonographic features of a rhabdoid tumor of the kidney


Fuchs, I.B., Henrich, W., Kalache, K.D., Lippek, F. and Dudenhausen, J.W. (2004) Prenatal sonographic features of a rhabdoid tumor of the kidney. Ultrasound in Obstetrics and Gynecology, 23, (4), 407-410. (doi:10.1002/uog.1022).

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Original Publication URL: http://dx.doi.org/10.1002/uog.1022

Description/Abstract

Rhabdoid tumors of the kidney are highly lethal malignancies of infancy. We report the prenatal detection of a renal rhabdoid tumor with mesoblastic components in a fetus at 27 weeks of gestation. The tumor presented as a large mass in the left renal area and there was concomitant massive polyhydramnios. Though the sonographic features alone did not allow distinction from a benign lesion, the aggressive tumor growth indicated malignancy. Amniotic fluid cytology was performed but failed to confirm the diagnosis. Corticosteroids were administered for lung maturation. Tocolysis, including betamimetics, magnesium and indomethacin, was performed to prevent premature labor. Additionally, serial amniodrainage was performed. At 30 weeks of gestation fetal hydrops developed and a Cesarean section was performed. After delivery, ventilation of the preterm infant was insufficient due to diaphragm elevation by the huge tumor, requiring immediate tumor surgery. However, though ventilation was improved the infant died of cardiac failure 4 h after surgery.

Item Type: Article
Additional Information: Case Report
ISSNs: 0960-7692 (print)
Related URLs:
Keywords: fetal, kidney, prenatal ultrasound, rhabdoid
Subjects: R Medicine > RG Gynecology and obstetrics
R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: University Structure - Pre August 2011 > School of Medicine > Developmental Origins of Health and Disease
ePrint ID: 25506
Date Deposited: 11 Apr 2006
Last Modified: 27 Mar 2014 18:14
URI: http://eprints.soton.ac.uk/id/eprint/25506

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