The 'gold standard' for optimal fetal growth and development

Godfrey, K.M. (2001) The 'gold standard' for optimal fetal growth and development. Journal of Pediatric Endocrinology and Metabolism, 14, (Supplement 6), 1507-1513.


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It is now becoming accepted that birth size per se is too crude an outcome measure to be used for the assessment of optimal intrauterine growth and development, and that a new vision of optimal fetal development is required for the 21st century. This will need to take account of both short- and long-term outcomes, to recognize that maternal body composition and diet can have long-term effects without necessarily affecting size at birth, and to take account of important interactions between the pre- and postnatal environments. At present, our understanding is limited and new definitions should only be considered as working hypotheses. Nonetheless, it is possible to begin to set out a framework for defining optimal fetal growth and development. This acknowledges the importance of developmental adaptations to alterations in the nutrient and hormonal milieu in utero and could have a major impact on human health in the century to come.

Item Type: Article
Additional Information: Supplement 6
ISSNs: 0334-018X (print)
Related URLs:
Subjects: R Medicine > RG Gynecology and obstetrics
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions : University Structure - Pre August 2011 > School of Medicine > Developmental Origins of Health and Disease
ePrint ID: 25549
Accepted Date and Publication Date:
Date Deposited: 07 Apr 2006
Last Modified: 31 Mar 2016 11:47

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