Off-pump coronary artery surgery

Heames, R. M., Gill, R. S., Ohri, S. K. and Hett, D. A. (2002) Off-pump coronary artery surgery. Anaesthesia, 57, (7), 676-685. (doi:10.1046/j.1365-2044.2002.02613.x).


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Cardiopulmonary bypass has several associated deleterious effects that include a systemic inflammatory response, coagulopathy, central nervous system complications and a variable degree of end-organ damage. The recent upsurge in interest in 'beating-heart' surgery attempts to avoid these deleterious effects. Advances in surgical technique, such as the use of intracoronary shunts and the Octopus retractor, have made beating-heart surgery a reality. The challenges for the anaesthetist are greater than for coronary artery surgery using cardiopulmonary bypass, and whilst some advantages are proven, such as the lack of the inflammatory response and the decreased need for blood or blood products, others have yet to be proved and there is a need for further research. The advantages and disadvantages need to be evaluated in randomised studies in order to confirm the safety and efficacy of these new techniques in terms of long-term graft patency and decreased morbidity.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1046/j.1365-2044.2002.02613.x
ISSNs: 0003-2409 (print)
Related URLs:
Keywords: anaesthesia, cardiovascular, surgery, cardiovascular
Subjects: R Medicine > RD Surgery
R Medicine
Divisions : University Structure - Pre August 2011 > School of Medicine > Developmental Origins of Health and Disease
ePrint ID: 25603
Accepted Date and Publication Date:
Date Deposited: 11 Apr 2006
Last Modified: 31 Mar 2016 11:47

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